DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rcc1 and AT1G69710

DIOPT Version :9

Sequence 1:	NP_523943.1	Gene:	Rcc1 / 38669	FlyBaseID:	FBgn0002638	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	NP_177129.2	Gene:	AT1G69710 / 843307	AraportID:	AT1G69710	Length:	1041	Species:	Arabidopsis thaliana

Alignment Length:	454	Identity:	123/454 - (27%)
Similarity:	183/454 - (40%)	Gaps:	103/454 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 NNNNAGEA--------EQQPPKAKRARIAFHLELPKRRTV------------------LGNVLVC 47
            :|||..||        ...|...:.:.:.|....|.|.::                  ||:|.|.
plant   201 SNNNQTEASGNLFCPFSPTPANVENSNLRFSTNDPFRLSLSSAVSTSSHGSYHEDFDALGDVFVW 265

  Fly    48 GN--GDVGQLGLG-------EDILERKRLSPVAGIPDAVDISAGGMHNLVLTKSGDIYSFGCNDE 103
            |.  .|....|.|       ||.|..|.|.... :.||.:|:.|..|.:::||.|:|:|:|....
plant   266 GESISDGVLSGTGNSLNSTTEDALLPKALESTI-VLDAQNIACGKCHAVLVTKQGEIFSWGEGKG 329

  Fly   104 GALGRDTSEDGSESKPDLID----LPGKALCISAGDSHSACLLEDGRVFAWGSFRDSHGNMGLTI 164
            |.||.....|.  .||..|.    |..|:|  :.||.|:..:.:.|.:::||   |...|:.|..
plant   330 GKLGHGLETDA--QKPKFISSVRGLGFKSL--ACGDFHTCAITQSGDLYSWG---DGTHNVDLLG 387

  Fly   165 DGN-------KRTPIDLMEGTVCCSIASGADHLVILTTAGKVFTVGCAEQGQLGRLSERSISGEG 222
            .||       ||...|| :|.....:|.|..|..::.::|::||.|....|.||....||.|
plant   388 HGNESSCWIPKRVTGDL-QGLYVSDVACGPWHTAVVASSGQLFTFGDGTFGALGHGDRRSTS--- 448

  Fly   223 RRGKRDLLRPTQLIITRAKPFEAIW-------ATNYCT--FMRESQTQVI-WATGLNNFKQLAH- 276
              ..|::.....||:|:...  .:|       .||..:  .:..|:.||. |..|...  ||.|
plant   449 --VPREVESLIGLIVTKVAC--GVWHTAAVVEVTNEASEAEVDSSRGQVFTWGDGEKG--QLGHG 507

  Fly   277 --ETKGKEFALTP---IKTELKDIRHIAGGQHHTVILTTDLKCSVVGRPEYGRLGLGDVK----- 331
              :||     |.|   |....::|..:|.|...||..|:......:|...||:||....|
plant   508 DNDTK-----LLPECVISLTNENICQVACGHSLTVSRTSRGHVYTMGSTAYGQLGNPTAKGNFPE 567

  Fly   332 ----DVVEKPTIVKKLTEKIVSVGCGEVCSYAVTIDGKLYSWGSGVNNQLGVGDGDDELEPIVV 391
                |:||         ..:..:.||......:|...::|:||.|:|.|||.|:.:::.||.||
plant   568 RVEGDIVE---------ASVEEIACGSYHVAVLTSKSEIYTWGKGLNGQLGHGNVENKREPAVV 622

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rcc1	NP_523943.1	RCC1	42..89	CDD:278826	17/55 (31%)
		RCC1	92..141	CDD:278826	17/52 (33%)
		RCC1_2	131..158	CDD:290274	7/26 (27%)
		RCC1	144..193	CDD:278826	16/55 (29%)
		RCC1_2	182..209	CDD:290274	7/26 (27%)
		RCC1	363..414	CDD:278826	13/29 (45%)
AT1G69710	NP_177129.2	PH_PLC_plant-like	25..135	CDD:270171
		RCC1_2	354..381	CDD:290274	9/31 (29%)
		RCC1	370..422	CDD:278826	16/55 (29%)
		RCC1	425..474	CDD:278826	15/55 (27%)
		RCC1	491..537	CDD:278826	15/52 (29%)
		RCC1	543..591	CDD:278826	11/56 (20%)
		RCC1	596..643	CDD:278826	13/27 (48%)
		FYVE	646..714	CDD:214499
		DUF4200	838..936	CDD:290574
		BRX_N	896..>921	CDD:290432
		BRX	981..1035	CDD:285568
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820