DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rcc1 and AT5G19420

DIOPT Version :9

Sequence 1:	NP_523943.1	Gene:	Rcc1 / 38669	FlyBaseID:	FBgn0002638	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	NP_001190338.1	Gene:	AT5G19420 / 832062	AraportID:	AT5G19420	Length:	1139	Species:	Arabidopsis thaliana

Alignment Length:	639	Identity:	155/639 - (24%)
Similarity:	235/639 - (36%)	Gaps:	179/639 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 LGNVLVCGNG-DVGQLGLGE-----------DILERKRLSPVAGIPDAVDISAGGMHNLVLTKSG 93
            ||:|.:.|.| ..|.||.|.           |.|..|.|.... :.|..:|:.||.|.:::||.|
plant   302 LGDVFMWGEGIGEGVLGGGNHRVGSSLEIKMDSLLPKALESTI-VLDVQNIACGGQHAVLVTKQG 365

  Fly    94 DIYSFGCNDEGALGRDTSEDGSESKPDLIDLPGKAL------CISAGDSHSACLLEDGRVFAWGS 152
            :.:|:|...||.||...  |.:...|.|||    ||      .::.|:.||..:...|.::.||.
plant   366 ESFSWGEESEGRLGHGV--DSNVQHPKLID----ALNTTNIELVACGEYHSCAVTLSGDLYTWGK 424

  Fly   153 FRDSHGNMGLTIDGN-------KRTPIDLMEGTVCCSIASGADHLVILTTAGKVFTVGCAEQGQL 210
                 |:.|:...||       ||... ||||....|||.|..|..::|:||::||.|....|.|
plant   425 -----GDFGILGHGNEVSHWVPKRVNF-LMEGIHVSSIACGPYHTAVVTSAGQLFTFGDGTFGVL 483

  Fly   211 GRLSERSI-------SGEGRRGKRDLLRPTQLIITRAKPFEAIWAT-------------NYCTFM 255
            |....:|:       |.:|.|..|...              .:|.|             :.|:
plant   484 GHGDRKSVFIPREVDSLKGLRTVRAAC--------------GVWHTAAVVEVMVGSSSSSNCS-- 532

  Fly   256 RESQTQVIWATGLNNFKQLAHETKGKEFALTPIKTELK-DIRHIAGGQHHTVILTTDLKCSVVGR 319
              |.....|..|  :..:|.|..|..:...|.:...:: :...:|.|...||.|||......:|.
plant   533 --SGKLFTWGDG--DKSRLGHGDKEPKLVPTCVAALVEPNFCQVACGHSLTVALTTSGHVYTMGS 593

  Fly   320 PEYGRLGLGDVKDVVEKPTIVK-KLTEKIV-SVGCGEVCSYAVTIDGKLYSWGSGVNNQLGVGDG 382
            |.||:||.......|  ||.|. ||.:..| .:.||......:|...::|:||.|.|.:||.||.
plant   594 PVYGQLGNPHADGKV--PTRVDGKLHKSFVEEIACGAYHVAVLTSRTEVYTWGKGSNGRLGHGDA 656

  Fly   383 DDELEPIVVVS----------------------KNTQGKHMLLASGGGQHAIFLVK--------- 416
            ||...|.:|.|                      |...|....:.||..|...|..|
plant   657 DDRNSPTLVESLKDKQVKSIACGSNFTAAVCLHKWASGMDQSMCSGCRQPFNFKRKRHNCYNCGL 721

  Fly   417 ------ADKQDQK------ENVPVKV----------------SGSSSISKKDKTPPQDNVDKEAE 453
                  ::|:..|      .|.|.:|                |..||:|::      ::|::.::
plant   722 VFCHSCSNKKSLKACMAPNPNKPYRVCDRCFNKLKKAMETDPSSHSSLSRR------ESVNQGSD 780

  Fly   454 NVDKQEQKENLP-------------AKASTSSKKNK---------TP-PQDNADKEAENVDKQEQ 495
            .:|:.|:.:...             .:..:.|||||         :| |...:.:.:.|:.|...
plant   781 AIDRDEKLDTRSDGQLARFSLLEPMRQVDSRSKKNKKYEFNSSRVSPIPSGGSHRGSLNITKSFN 845

  Fly   496 KENLPAKASTSSKKI--KTPPQDDAAEEVEEESAQEPTPKKAKKPAAKRGGKKT 547
                  ....||||.  .:.|....|.......::.|:|.::..|.....|..|
plant   846 ------PTFGSSKKFFSASVPGSRIASRATSPISRRPSPPRSTTPTPTLSGLTT 893

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rcc1	NP_523943.1	RCC1	42..89	CDD:278826	17/58 (29%)
		RCC1	92..141	CDD:278826	17/54 (31%)
		RCC1_2	131..158	CDD:290274	6/26 (23%)
		RCC1	144..193	CDD:278826	18/55 (33%)
		RCC1_2	182..209	CDD:290274	11/26 (42%)
		RCC1	363..414	CDD:278826	19/72 (26%)
AT5G19420	NP_001190338.1	PH_PLC_plant-like	57..164	CDD:270171
		RCC1_2	348..377	CDD:290274	10/28 (36%)
		RCC1	365..413	CDD:278826	17/53 (32%)
		RCC1	416..466	CDD:278826	18/55 (33%)
		RCC1	470..518	CDD:278826	14/61 (23%)
		RCC1	534..582	CDD:278826	10/49 (20%)
		RCC1	585..634	CDD:278826	15/50 (30%)
		RCC1	639..686	CDD:278826	14/46 (30%)
		FYVE	690..757	CDD:279674	12/66 (18%)
		Tup_N	906..956	CDD:285748
		BRX_N	949..984	CDD:290432
		BRX_assoc	990..1057	CDD:293233
		BRX	1064..1118	CDD:285568
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820