DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rcc1 and AT3G03790

DIOPT Version :9

Sequence 1:	NP_523943.1	Gene:	Rcc1 / 38669	FlyBaseID:	FBgn0002638	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	NP_001189802.1	Gene:	AT3G03790 / 821145	AraportID:	AT3G03790	Length:	1099	Species:	Arabidopsis thaliana

Alignment Length:	605	Identity:	131/605 - (21%)
Similarity:	223/605 - (36%)	Gaps:	170/605 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 AFHLELPKRRT-----------VLG--------NVLVCGNGDVGQLGLGEDILERKRLSPVAGIP 74
            :|.||..|.||           |:|        .|...|||...|||.|...:::        :|
plant   121 SFTLEDIKLRTPVDLVSGPVAQVIGEQQSSVATEVFSWGNGANYQLGTGNQHVQK--------VP 177

  Fly    75 DAVD---------ISAGGMHNLVLTKSGDIYSFGCNDEGALGRDTSEDGSESKPDLIDLPGKAL- 129
            ..||         :||...|::.::..|::|::|....|.||.  .|....|....:..|.:.:
plant   178 GRVDSLHGCFIKLVSAAKFHSVAISTHGEVYTWGFGRGGRLGH--PEFDIHSGQAAVITPRQVIS 240

  Fly   130 --------CISAGDSHSACLLEDGRVFAWGSFRDSHGNMGLTIDGNKRTP--IDLMEGTVCCSIA 184
                    .::|...|:....|.|.|:.|||.|:  |.:|.|....:.||  :..::..: .:::
plant   241 GLGSRRVKAVAAAKHHTVIATEGGDVYTWGSNRE--GQLGYTSVDTQATPRKVTSLKAKI-VAVS 302

  Fly   185 SGADHLVILTTAGKVFTVGCAEQGQLGRLSERSISGEGRRGKRDLLRPTQLIITRAKPFEAIWAT 249
            :...|..:::..|:|||.||.::||||..:..|.|.         ..|..:...:.|.|.||.::
plant   303 AANKHTAVVSDCGEVFTWGCNKEGQLGYGTSNSASN---------YSPRLVDYLKGKVFTAIASS 358

  Fly   250 NYCTFMRESQTQV-IWATGL---------NNFKQLAHETKGKEFALTPIKTELKDIRHIAGGQHH 304
            .|.|.:..:..:| .|...|         .|.|: |..|........|::     :..||.|..|
plant   359 KYHTLVLRNDGEVYTWGHRLVTPRRVIISRNLKK-AGNTLLNFHRRRPLR-----LTAIAAGMVH 417

  Fly   305 TVILTTD------------LKC----SVVGRPEYGRLGLGDVKDVVEKPTIVKKLTEKIVSVGCG 353
            ::.|..|            |:|    |:.|:                          .:||:..|
plant   418 SLALAEDGAFFYWVSSDSNLRCQQLHSLHGK--------------------------TVVSISAG 456

  Fly   354 EVCSYAVTIDGKLYSWGSGVNNQLGVGDGDDELEPIVVVSKNTQGKHMLLASGGGQHAIFLVKAD 418
            :..:.|||..|::|.| .|.|.: .:......|..:...:....|:..||..|...|..:
plant   457 KYWASAVTSTGEVYMW-DGKNGK-DIAPSLSRLHNLKRATTVAVGETHLLVVGSLYHPAY----- 514

  Fly   419 KQDQKENVPVKVSGSSSISKKDKTPPQDNV---------DKEAENVDKQEQKEN-----LPAKAS 469
                   .|:.:..|.:: :.||...::|.         |.|:.||.:..|.:|     :|:..|
plant   515 -------APIVLKKSQTL-QADKCREEENEELDEGFMFDDVESVNVLQSVQYDNPKERIVPSLKS 571

  Fly   470 TSSK---------KNKTPPQDNADK-EAENVDKQEQK---ENLPAKASTSSKKIKTPPQDDAA-- 519
            ...|         :|.....:.||. .||::.|..:.   .||....:.|.:.|.....|..|
plant   572 LCEKVAAECIVEPRNAIQLLEIADSLGAEDLKKYCEDIVIRNLDFILTFSPQSIANTSPDVLANL 636

  Fly   520 EEVEEESAQE-------PTP 532
            |::.::.:.|       |||
plant   637 EKLLDDRSSETWSSRPLPTP 656

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rcc1	NP_523943.1	RCC1	42..89	CDD:278826	15/63 (24%)
		RCC1	92..141	CDD:278826	11/57 (19%)
		RCC1_2	131..158	CDD:290274	9/26 (35%)
		RCC1	144..193	CDD:278826	12/50 (24%)
		RCC1_2	182..209	CDD:290274	7/26 (27%)
		RCC1	363..414	CDD:278826	11/50 (22%)
AT3G03790	NP_001189802.1	ANK	29..137	CDD:238125	6/15 (40%)
		Ank_2	29..126	CDD:289560	2/4 (50%)
		ANK repeat	29..59	CDD:293786
		ANK repeat	61..92	CDD:293786
		ANK repeat	95..126	CDD:293786	2/4 (50%)
		RCC1	154..201	CDD:278826	14/54 (26%)
		RCC1	205..259	CDD:278826	11/55 (20%)
		RCC1	264..311	CDD:278826	12/49 (24%)
		RCC1	315..365	CDD:278826	19/58 (33%)
		SPOP_C_like	586..>615	CDD:269810	7/28 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820