DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rcc1 and rcbtb2

DIOPT Version :9

Sequence 1:	NP_523943.1	Gene:	Rcc1 / 38669	FlyBaseID:	FBgn0002638	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	XP_005173422.1	Gene:	rcbtb2 / 794652	ZFINID:	ZDB-GENE-071016-3	Length:	527	Species:	Danio rerio

Alignment Length:	287	Identity:	76/287 - (26%)
Similarity:	126/287 - (43%)	Gaps:	43/287 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 CSIASGADHLVILTTAGKVFTVGCAEQGQLGRLSERSISGEGRRGKRDLLRPTQLIITRAKPFEA 245
            |...|.|:..:.:|...:||.:|....|.|| |.:...:.|.||  .|:|...::|
Zfish    25 CVFGSAANEAIYVTVNDEVFALGTNCSGCLG-LGDTQSTIEPRR--IDILCGKKII--------- 77

  Fly   246 IWATNYCT---FMRESQTQVIWATGLNNFKQLAHETKGKEFALTP--IKTEL--KDIRHIAGGQH 303
              :.:|.|   .:..:....::|.|.|.:.||.:.|  ....|||  :.|.|  |.:..::.|.|
Zfish    78 --SLSYGTGPHVVIATADGEVYAWGHNGYSQLGNGT--TNHGLTPALVSTNLIGKRVTEVSCGSH 138

  Fly   304 HTVILTTDLKCSVVGRPEYGRLGLGDVKDVVEKPTIVKKLTEK-IVSVGCGEVCSYAVTIDGKLY 367
            ||:.||||.:....|....|::|.|...:......:...|..| :|::.||::||.||..:|:.|
Zfish   139 HTIALTTDGEVYAWGYNNSGQVGSGSTANQPTPRRVSSCLQNKVVVNIACGQLCSMAVLDNGETY 203

  Fly   368 SWGSGVNNQLGVGDGDDELEPIVVVSKNTQGKHMLLASGGGQHAIFLVK--------ADKQDQKE 424
            .||...|.|||:|:..::..|..:.:  .||.:::..:.|..|.:.|..        |:...|..
Zfish   204 GWGYNCNGQLGLGNNGNQQTPCRIAA--LQGINIIQVACGYAHTLALTDEGFVYSWGANSYGQLG 266

  Fly   425 NVPVKVSGSSSISKKDKTPPQDNVDKE 451
                  :|:.|   ....|...|:|||
Zfish   267 ------TGNKS---NQAVPTLINMDKE 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rcc1	NP_523943.1	RCC1	42..89	CDD:278826
		RCC1	92..141	CDD:278826
		RCC1_2	131..158	CDD:290274
		RCC1	144..193	CDD:278826	3/11 (27%)
		RCC1_2	182..209	CDD:290274	6/26 (23%)
		RCC1	363..414	CDD:278826	14/50 (28%)
rcbtb2	XP_005173422.1	RCC1	40..89	CDD:278826	15/62 (24%)
		RCC1	93..143	CDD:278826	16/51 (31%)
		RCC1	146..196	CDD:278826	12/49 (24%)
		RCC1	199..248	CDD:278826	14/50 (28%)
		RCC1	251..299	CDD:278826	9/43 (21%)
		BTB	364..460	CDD:279045
		BTB	371..463	CDD:197585
		SPOP_C_like	463..521	CDD:269810
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576192
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840