Protein Alignment Rcc1 and als2

DIOPT Version :10

• Sequence 1: NP_523943.1
• Gene: Rcc1 / 38669
• FlyBaseID: FBgn0002638
• Length: 547
• Species: Drosophila melanogaster
• Sequence 2: XP_004917812.2
• Gene: als2 / 779575
• XenbaseID: XB-GENE-922619
• Length: 1640
• Species: Xenopus tropicalis
• Alignment Length: 489
• Identity: 91/489 - (18%)
• Similarity: 151/489 - (30%)
• Gaps: 176/489 - (35%)

  Fly    79 ISAGGMHNLVLTKSGDIYSFGCNDEGALGRDTSEDGSESKPDLIDLPG---------KALCISAG 134
            :.||..||..:|:||.:|.:|.|..|...  .:...|..||..|.:..         :.:.:|.|
 Frog    94 VGAGSYHNGAVTESGMVYMWGENTAGQCA--IANYPSIPKPTAITITDQETTPPRWVRTIQLSCG 156

  Fly   135 DSHSACLLEDGRVFAWGSFRDSHG-NMGL---TIDGNKRTPIDLMEGTVCCSIASGA-------- 187
            :.|:..|.....::||||     | .:||   |....|...::.:.|.:...:..||
 Frog   157 EEHTLALSVSREIWAWGS-----GCQLGLITTTFPVIKPQKVEHLSGRIVLQVVCGAFHSLALVQ 216

  Fly   188 ----------------------------DHLVILTTAGKVFTVGCAE--------QGQLG----- 211
                                        ||::|.........|..||        |...|
 Frog   217 CPIAQDLKPVPERCNHCSQLLITMTDKEDHVIISDAHCCPLGVMLAESHPGSRSNQSSFGLSVKS 281

  Fly   212 ----RLSERSISGEGRRGKRDLLRPTQLIITRAKPF-----EAIWATNYCTFMRESQTQVIWATG 267
                .:|..:::.|.:...:..|.....:.|.|..|     ..|:..:..|....||::.....|
 Frog   282 VKKEHISHSAMTHEEKETSQQYLESDTELGTDAASFCETETSQIFGKSNGTIPAPSQSEQYLKDG 346

  Fly   268 LNNFKQLAHETKGKEFALTPIKTELKDIRHIAGGQHHTVILTTDL-----KCS------VVGRPE 321
            :....||..:            ..|:::...||..  |.|.|:.|     .|:      |....|
 Frog   347 MAEVTQLQEQ------------NPLENVSETAGSS--TAIATSGLNSLMVSCASAVSVRVAATCE 397

  Fly   322 YGRLGLGDV-------------------------KDVVEK------------------------- 336
            .|.|.|..|                         ||..|:
 Frog   398 AGALSLKKVMNFYSGSLCDPGVQQGVSSSAQDGLKDSREEQVKLESMQGKKSSSLVDIREEEADA 462

  Fly   337 ---------------PTIVKKL------TEKIVSVGCGEVCSYAVTIDGKLYSWGSGVNNQLGVG 380
                           |.:::|:      |..:.....||......::..:::|||.|...|||.|
 Frog   463 GNRRLSLPGLLSQVSPRLLRKVGRARMRTVALTPTNSGEADVLLPSLKTEVWSWGRGKEGQLGHG 527

  Fly   381 DGDDELEPIVVVSKNTQGKHMLLASGGGQHAIFL 414
            |....|:|:.|  ::..||.::..:.|..|::.|
 Frog   528 DVLPRLQPLCV--RSMDGKEVIQLAAGSHHSLAL 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rcc1	NP_523943.1	ATS1	42..389	CDD:444065	84/462 (18%)
		Borrelia_P83	<419..>508	CDD:114011
als2	XP_004917812.2	ATS1	<18..217	CDD:444065	31/129 (24%)
		ATS1	<512..666	CDD:444065	17/50 (34%)
		RhoGEF	678..867	CDD:470622
		PH_alsin	888..993	CDD:241423
		COG4642	<1028..1185	CDD:443680
		VPS9	1537..1639	CDD:460489