DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rcc1 and herc5.1

DIOPT Version :9

Sequence 1:	NP_523943.1	Gene:	Rcc1 / 38669	FlyBaseID:	FBgn0002638	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	XP_017211386.1	Gene:	herc5.1 / 559981	ZFINID:	ZDB-GENE-090311-56	Length:	884	Species:	Danio rerio

Alignment Length:	363	Identity:	91/363 - (25%)
Similarity:	145/363 - (39%)	Gaps:	104/363 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 GNVLVCGNGDVGQLGLGED---ILERKRLSPVAGIPDAVDISAGGMHNLVLTKSGDIYSFGCNDE 103
            |.:.|.|...:|||||.::   ....:.|..:.|||.| .|||||.|:.||:.||.::.:|.|..
Zfish    29 GQLFVWGENALGQLGLRKEQAGTQSPRHLQSLCGIPVA-QISAGGNHSFVLSLSGVVFGWGGNSA 92

  Fly   104 GALGRDTSEDGSESKPDLID--LPGKALCISAGDSHSACLLEDGRVFAWG----------SFRDS 156
            |.||...:.|  ...|.:::  ...|.:.||.|..|:|.|.:.|.||.:|          ||:|.
Zfish    93 GQLGLGDTTD--RFVPTVVNSLKRKKIVSISCGGEHTAALAKGGTVFTFGSGGFGQLGHNSFKDE 155

  Fly   157 HGNMGLTIDGNKRTPIDLMEGTVCCSIASGADHLVILTTAGK-VFTVGCAEQGQLGRLSERSISG 220
            |         :.|...:|. |:....:..|.:|.::.|.:.| :::.||..||||         |
Zfish   156 H---------HPRLVAELW-GSKVSQVTCGRNHTLVSTASPKLIYSFGCGMQGQL---------G 201

  Fly   221 EGRRGKRDLLRPTQLIITRAKPFEAIWATNYCTFMRESQTQVIWATGLNN-----FKQLAHE--- 277
            .|.:.|:.:..|..      :|.|         :..|...|.:.| |.|:     ||:|.:|
Zfish   202 NGEQVKQSVPLPVD------QPTE---------YNDEYTIQKLVA-GENHSFALYFKELGNEANP 250

  Fly   278 --TKG-----------KEFALTPIKTELKDIRHIAGG-----------QHHTVILTTDLKCSVVG 318
              |:|           .|....|.|. :||::.:...           :|.....|::
Zfish   251 DPTRGIMTFDNGMIEQCECGKDPRKA-IKDLKKVFSSAASLNGSFLKTRHDGHYQTSE------- 307

  Fly   319 RPEYGRLGLGDVKDVVEK--------PTIVKKLTEKIV 348
              ||..|..|.|:..:..        .|::|.|.|.::
Zfish   308 --EYCGLDFGLVESSIATLSRNERLISTVLKVLQESLL 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rcc1	NP_523943.1	RCC1	42..89	CDD:278826	19/49 (39%)
		RCC1	92..141	CDD:278826	15/50 (30%)
		RCC1_2	131..158	CDD:290274	13/36 (36%)
		RCC1	144..193	CDD:278826	13/58 (22%)
		RCC1_2	182..209	CDD:290274	7/27 (26%)
		RCC1	363..414	CDD:278826
herc5.1	XP_017211386.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010