DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rcc1 and Rcbtb1

DIOPT Version :9

Sequence 1:	NP_523943.1	Gene:	Rcc1 / 38669	FlyBaseID:	FBgn0002638	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	NP_001101850.1	Gene:	Rcbtb1 / 361050	RGDID:	1308467	Length:	531	Species:	Rattus norvegicus

Alignment Length:	337	Identity:	79/337 - (23%)
Similarity:	137/337 - (40%)	Gaps:	64/337 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 GNVLVCGNGDVGQLGLGEDILERKRLSPVAG-----IPDAVDISAGGMHNLVLTKSGDIYSFGCN 101
            |.|...|:....|||.|   ...:.::|:..     :...|:::.|..|::.|...|:::::|.|
  Rat    94 GVVYAWGHNGYSQLGNG---TTNQGIAPIQVCTNLLVKQVVEVACGSHHSMALAADGELFAWGYN 155

  Fly   102 DEGALGR-DTSEDGSESKPDLIDLPGKALCISAGDSHSACLLEDGRVFAWGSFRDSHGNMGLTID 165
            :.|.:|. .|:...:..|........|.:.|:.|.:.|..:|:.|.|:.||  .:.:|.:||..:
  Rat   156 NCGQVGSGSTANQPTPRKVTNCLHTKKVVNIACGQTSSMAVLDSGEVYGWG--YNGNGQLGLGNN 218

  Fly   166 GNKRTPIDL--MEGTVCCSIASGADHLVILTTAGKVFTVGCAEQGQLGRLSERSISGEGRRGKRD 228
            ||:.||:.:  :.|.....|..|..|.:.||..|.::..|....||||..|           |.:
  Rat   219 GNQLTPVRVAALHGVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGS-----------KNN 272

  Fly   229 LLRPTQLIITRAKPFEAIWATNYCTFMRESQTQ----VIWATGLNNFKQLAHETKGKEFALTPIK 289
            ||.|||:::.:.:..|.  |..:.|....::||    .:|.           :.:|:...|
  Rat   273 LLSPTQIMVEKERVIEI--AACHSTHTSAAKTQGGHVYMWG-----------QCRGQSVIL---- 320

  Fly   290 TELKDIRHIAGGQHHTVILTTDLKCSVVGRPEYG-RLGLGDVKDVVEKPTIVKKLTEKIVSVGCG 353
                        .|.|....||...:..|.|... ||...:.:|.:   |:.:.|.::..|   .
  Rat   321 ------------PHLTHFSCTDDVFACFGTPAVSWRLLSVEHEDFL---TVAESLKKEFDS---P 367

  Fly   354 EVCSYAVTIDGK 365
            |.......||||
  Rat   368 ETADLKFRIDGK 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rcc1	NP_523943.1	RCC1	42..89	CDD:278826	11/51 (22%)
		RCC1	92..141	CDD:278826	11/49 (22%)
		RCC1_2	131..158	CDD:290274	8/26 (31%)
		RCC1	144..193	CDD:278826	15/50 (30%)
		RCC1_2	182..209	CDD:290274	7/26 (27%)
		RCC1	363..414	CDD:278826	3/3 (100%)
Rcbtb1	NP_001101850.1	RCC1	42..89	CDD:395335
		ATS1	<91..363	CDD:227511	73/316 (23%)
		BTB_POZ_RCBTB1_CLLD7	350..466	CDD:349662	9/36 (25%)
		BACK_RCBTB1	466..531	CDD:350603
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337065
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840