DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rcc1 and CG7420

DIOPT Version :9

Sequence 1:	NP_523943.1	Gene:	Rcc1 / 38669	FlyBaseID:	FBgn0002638	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	NP_001259871.1	Gene:	CG7420 / 33332	FlyBaseID:	FBgn0031344	Length:	388	Species:	Drosophila melanogaster

Alignment Length:	381	Identity:	99/381 - (25%)
Similarity:	153/381 - (40%)	Gaps:	68/381 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 VLVCGNGDVGQLGLG---EDILERKRLSPVAGIPDAVD-ISAGGMHNLVLTKSGDIYSFGCNDEG 104
            |...|....||||||   |..:..:|::..:..|..|. |..||.|.|:|..||.|::.|.|:.|
  Fly     3 VYAWGANSHGQLGLGFESELCMTPQRVAKCSFAPAQVRLIRGGGGHVLILDTSGRIHACGWNNRG 67

  Fly   105 ALGRDTSED-GSESKPDLI------DLPGKALCISAGDSHSACLLEDGRVFAWGSFRDSHGNMGL 162
            .||.|::|: .||.|  :|      |:|.:.  ||.|...|..:....|:|.|||  ::...:|:
  Fly    68 QLGLDSTEECHSEFK--MIPTEYFGDVPVET--ISCGWDISGAITLTKRLFVWGS--NAFQQLGI 126

  Fly   163 TIDG----NKRTPIDLMEGTVCCSIASGADHLVILTTAGKVFTVGCAEQGQLGRLS-------ER 216
            ...|    .:..|:.|........|:.|..|..:||...|::.        .|||.       |.
  Fly   127 CQRGFTAVRRPMPVKLPREEPAQRISFGLRHCAVLTQDNKIYV--------FGRLRIMDPPPIEL 183

  Fly   217 SISG----EGRRGKRDLLRPTQLIITRAKPFEAIWATNY----CTFMRES---QTQVIWATGLNN 270
            .|:.    .....|..:..|.:|.|.....     ..|:    |..:.|:   .|:.|...|.|.
  Fly   184 DITATCLHRCNTVKIQVHNPNELRIVSISS-----GQNHMVLKCADLSETGGGSTKRILTLGDNK 243

  Fly   271 FKQLAHETKGKEFALTPIKTELKDIRHIAGGQHHTVILTTDLKCSVVGRPEYGRLGLGDVKDVVE 335
            |.|    :...:|.        :|:|.:|.|..|...:..:.:..|.||..||:||:|...:...
  Fly   244 FGQ----SNAFQFE--------EDVRQLAVGWTHNAAVLKNNEILVWGRNCYGQLGMGSFSEQQA 296

  Fly   336 KPTIVK-KLTEK--IVSVGCGEVCSYAVTIDGKLYSWGSGVNNQLGVGDGDDELEP 388
            .||.:: ||.|.  ...:..|.......|..|::|:||...:...| .:..:.|.|
  Fly   297 IPTPLRLKLPEDQGPARIHMGAEHGLLRTTAGEVYTWGWNEHGNCG-NNSTENLHP 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rcc1	NP_523943.1	RCC1	42..89	CDD:278826	17/48 (35%)
		RCC1	92..141	CDD:278826	20/55 (36%)
		RCC1_2	131..158	CDD:290274	9/26 (35%)
		RCC1	144..193	CDD:278826	12/52 (23%)
		RCC1_2	182..209	CDD:290274	6/26 (23%)
		RCC1	363..414	CDD:278826	7/26 (27%)
CG7420	NP_001259871.1	RCC1	2..52	CDD:278826	17/48 (35%)
		RCC1	55..107	CDD:278826	20/55 (36%)
		RCC1	112..161	CDD:278826	12/50 (24%)
		RCC1_2	256..285	CDD:290274	8/28 (29%)
		RCC1	274..320	CDD:278826	14/45 (31%)
		RCC1	328..>348	CDD:278826	5/20 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442609
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840