DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rcc1 and CG3862

DIOPT Version :9

Sequence 1:	NP_523943.1	Gene:	Rcc1 / 38669	FlyBaseID:	FBgn0002638	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster

Alignment Length:	456	Identity:	113/456 - (24%)
Similarity:	164/456 - (35%)	Gaps:	122/456 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PRRKALTNNNNAGEAEQQPPKAKRARIAFHLELPKR---RTVLGNVLVCGNGDVGQLGL------ 57
            |.|...:|||...:.        .|...|.:....|   .|:.|:.|   |.| .|||.
  Fly    77 PTRLQFSNNNEITDV--------AAGYGFTVYAVNRDDGETLFGSGL---NTD-SQLGFQVKGNP 129

  Fly    58 ----GEDIL---ERKRLSPVAGIPD----AVDISAGGMHNLVLTKSGDIYSFGCNDEGALGRDTS 111
                ..|::   ...:|..|.|..|    ...:|||..|.:|||::|.|::.|.|..|..||...
  Fly   130 NDPANLDVIIYPTAIKLPRVQGETDEDMRVKSMSAGRAHLVVLTQNGTIFTLGNNSYGQCGRSII 194

  Fly   112 EDGSESKPDLI------DLPGK---ALCISAGDSHSACLLEDGRVF--AWGSFRDSHGNMGLTID 165
            |:...||..||      |:.||   .:.:..|..||..|.:.||::  .||:       .|.|..
  Fly   195 EEERYSKSALIHRISQEDICGKEDEVVQVECGQDHSMFLTKKGRIYTCGWGA-------DGQTGQ 252

  Fly   166 GNKRT--PIDLMEGTV----CCSIASGADHLVILTTAGKVFTVGCAEQGQL--GRLSERSISGEG 222
            ||..|  .|.|:.|.|    ...::..:|.::.|..||..|..|.:|.|||  ..|:|..|:
  Fly   253 GNYHTAGQITLIGGDVEKEKIVRLSCSSDCVLALNEAGDAFGWGNSEYGQLDDSELAETQIN--- 314

  Fly   223 RRGKRDLLRPTQLIITRA--KPFEAIWATNYCTFMRESQTQVIWATGLNNFKQLAHETKGKEFAL 285
                    .|..|.:|::  |..:.....::|..:.:......|..|:..|.....:|...:..|
  Fly   315 --------IPRALKLTKSIGKIKDVAAGGSFCMALNDQGLVYTWGFGILGFGPFVEQTSKPQHLL 371

  Fly   286 TPIKTELKDIRHIAGGQHHTVILTTDLKCSVVGRPEYGRLGLGDVKDVVEKPTIVKKLTEKIVSV 350
            .|:                                 :||      .|...:.|        :||:
  Fly   372 PPL---------------------------------FGR------NDFSNETT--------VVSI 389

  Fly   351 GCGEVCSYAVTIDGKLYSWGSGVNNQLGVGDGDDELEPIVVVSKNTQGKHMLLASGGGQHAIFLV 415
            |||.....||..||.|:.||......||:|...|:..|....   ..||...:|. |..|.|.|.
  Fly   390 GCGVFHMGAVNSDGDLFMWGKNRFGHLGLGHKKDQFFPFKAA---INGKVTKVAY-GVDHTIALC 450

  Fly   416 K 416
            |
  Fly   451 K 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rcc1	NP_523943.1	RCC1	42..89	CDD:278826	16/63 (25%)
		RCC1	92..141	CDD:278826	18/57 (32%)
		RCC1_2	131..158	CDD:290274	8/28 (29%)
		RCC1	144..193	CDD:278826	14/56 (25%)
		RCC1_2	182..209	CDD:290274	7/26 (27%)
		RCC1	363..414	CDD:278826	16/50 (32%)
CG3862	NP_608550.1	RCC1	43..99	CDD:278826	7/29 (24%)
		RCC1_2	159..188	CDD:290274	11/28 (39%)
		RCC1	175..233	CDD:278826	18/57 (32%)
		RCC1_2	220..249	CDD:290274	8/35 (23%)
		RCC1	236..286	CDD:278826	14/56 (25%)
		RCC1	290..341	CDD:278826	15/61 (25%)
		RCC1	345..395	CDD:278826	15/96 (16%)
		RCC1_2	386..414	CDD:290274	12/27 (44%)
		RCC1	402..449	CDD:278826	16/50 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442607
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840