DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rcc1 and Rccd1

DIOPT Version :9

Sequence 1:	NP_523943.1	Gene:	Rcc1 / 38669	FlyBaseID:	FBgn0002638	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	XP_006229517.1	Gene:	Rccd1 / 308760	RGDID:	1309901	Length:	378	Species:	Rattus norvegicus

Alignment Length:	414	Identity:	86/414 - (20%)
Similarity:	127/414 - (30%)	Gaps:	155/414 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 CGNGDVGQLGLGEDILERKRLSPVAGIPDAVDISAGGMHNLVLTKSGDI--------YSFGCND- 102
            ||.|.....|.|:..:...  .|:....|...:||...:..::|:.|.:        .:.||.|
  Rat    15 CGFGQALGSGNGQHAVHSP--EPLHAADDVCQVSASWSYTALVTRGGRVELSGSVSCAADGCRDV 77

  Fly   103 ----------------------------------------EGALGRDTSEDGSESKPDLIDL--- 124
                                                    .||..:...|.|||.:...:.|
  Rat    78 WASEGLLVVQRNKSGSGTELQAWVPGSALQGEPLWVQNLASGAKAQGEDEPGSEPRMGTLPLLPC 142

  Fly   125 ------PGKALC-----------ISAGDSHSACLLEDGRVFAWGSFRDSHGNMG---LTIDGNKR 169
                  |....|           :..|..|:..|.|.|:||:||..|  ||.:|   |..:...|
  Rat   143 ARAYMTPQPPFCQPLAPELRVRQLQLGAEHALLLCEAGQVFSWGGGR--HGQLGHGSLEAELEPR 205

  Fly   170 TPIDLMEGTVCCSIASGADHLVILTTAGKVFTVGCAEQGQLGRLSERSISGEGRRGKRDLLRPTQ 234
            . ::.::|.....:|:|..|.|.::..|.::..|..|.|||. |..||    |...|.
  Rat   206 L-LEALQGLRMAEVAAGGWHSVCVSETGDIYIWGWNESGQLA-LPTRS----GTEKKT------- 257

  Fly   235 LIITRAKPFEAIWATNYCTFMRESQTQVIWATGLNNFKQLAHETKGKEFALTPIKTELKDIRHIA 299
                                :||.      ||.||:     ...:|:|.||..:
  Rat   258 --------------------VREE------ATELND-----DGLRGEEAALADV----------- 280

  Fly   300 GGQHHTVILTTDLKCSVVGRPEYGRLGLGDVKDVVEKPTIVKKLTEKIVSVGCGEVCSYAVTIDG 364
            |...|.:.:          :|....|.|              .|....|...||...:..||..|
  Rat   281 GAPAHFIAI----------QPFPALLDL--------------PLGSDAVKASCGSRHTAVVTRTG 321

  Fly   365 KLYSWGSGVNNQLGVGDGDDELEP 388
            :||:||.|...|||..|.....:|
  Rat   322 ELYTWGWGKYGQLGHKDSTSSDQP 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rcc1	NP_523943.1	RCC1	42..89	CDD:278826	9/41 (22%)
		RCC1	92..141	CDD:278826	15/117 (13%)
		RCC1_2	131..158	CDD:290274	10/26 (38%)
		RCC1	144..193	CDD:278826	16/51 (31%)
		RCC1_2	182..209	CDD:290274	7/26 (27%)
		RCC1	363..414	CDD:278826	11/26 (42%)
Rccd1	XP_006229517.1	RCC1_2	163..192	CDD:290274	11/30 (37%)
		RCC1	180..228	CDD:278826	16/50 (32%)
		RCC1_2	218..244	CDD:290274	7/25 (28%)
		RCC1_2	305..333	CDD:290274	11/27 (41%)
		RCC1	321..368	CDD:278826	11/25 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337062
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840