DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rcc1 and Rcbtb2

DIOPT Version :9

Sequence 1:	NP_523943.1	Gene:	Rcc1 / 38669	FlyBaseID:	FBgn0002638	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	XP_038949091.1	Gene:	Rcbtb2 / 290363	RGDID:	735048	Length:	585	Species:	Rattus norvegicus

Alignment Length:	341	Identity:	82/341 - (24%)
Similarity:	131/341 - (38%)	Gaps:	76/341 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 TVLGNVLVCGNGDVGQLGLG--EDILERKRLSPVAGIPDAVDISAGGMHNLVLTKSGDIYSFGCN 101
            ||...:.|.|....|.||:|  :..:|.:||..:.|...|......|.|.::.|..|:::::|.|
  Rat    96 TVNDEIFVLGTNCSGCLGVGDIQSTIEPRRLDSLTGKKIASLSYGSGPHIVLATTDGEVFTWGHN 160

  Fly   102 DEGALGRDTSEDGSESKPDLIDLPGKALC-ISAGDSHSACLLEDGRVFAWGSFRDSHGNMGLTID 165
            ....||..|:..|........:|..|.:. ::.|..||..|..||.|||||  .::.|.:|....
  Rat   161 AYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWG--YNNSGQVGSGST 223

  Fly   166 GNKRTP---IDLMEGTVCCSIASGADHLVILTTAGKVFTVGCAEQGQLGRLSERSISGEGRRGKR 227
            .|:..|   ...::..|..|||.|....:.:...|:|:..|....||||.         |..|.
  Rat   224 ANQPIPRRVTGCLQNKVVMSIACGQMCSMAVVDTGEVYVWGYNGNGQLGL---------GSSGN- 278

  Fly   228 DLLRPTQLIITRAKPFEAIWATNYCTFMRESQTQVIWATGLNNFKQLAHETKGKEFALTPIKTEL 292
               :||...:.                                             ||..|:
  Rat   279 ---QPTPCRVA---------------------------------------------ALQGIR--- 292

  Fly   293 KDIRHIAGGQHHTVILTTDLKCSVVGRPEYGRLGLGDVKD-VVEKPTIVKKLTEKIVSV-GCGEV 355
              ::.:|.|..||::||.:.:....|...||:||.|:..: ....|.:|:|  ::|:.: .|...
  Rat   293 --VQRVACGYAHTLVLTDEGQIYAWGANSYGQLGTGNKSNQSYPTPVVVEK--DRIIEIAACHSA 353

  Fly   356 -CSYAVTIDGKLYSWG 370
             .|.|.:..|.:|.||
  Rat   354 HTSAAKSQGGHVYMWG 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rcc1	NP_523943.1	RCC1	42..89	CDD:278826	13/48 (27%)
		RCC1	92..141	CDD:278826	12/49 (24%)
		RCC1_2	131..158	CDD:290274	11/26 (42%)
		RCC1	144..193	CDD:278826	16/51 (31%)
		RCC1_2	182..209	CDD:290274	7/26 (27%)
		RCC1	363..414	CDD:278826	4/8 (50%)
Rcbtb2	XP_038949091.1	ATS1	<141..421	CDD:227511	69/296 (23%)
		BTB_POZ_RCBTB2_CHC1L	408..524	CDD:349663
		BACK_RCBTB2	521..585	CDD:350604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337058
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840