DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rcc1 and Zzef1

DIOPT Version :9

Sequence 1:	NP_523943.1	Gene:	Rcc1 / 38669	FlyBaseID:	FBgn0002638	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	XP_006246919.1	Gene:	Zzef1 / 287476	RGDID:	1311189	Length:	2965	Species:	Rattus norvegicus

Alignment Length:	237	Identity:	51/237 - (21%)
Similarity:	91/237 - (38%)	Gaps:	53/237 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   333 VVEKPTIVKKLTEKIVSVGCGEVCSYAVTID-GKLYSWGSGV---------NNQLGVGDGDDELE 387
            |...|.:.:||.:.:.|.|     ..|:..: .::||...|:         .:.:.:|:..:|..
  Rat  1345 VYRTPDLYEKLQKYVHSGG-----KIALPEEFSQVYSLADGIRIWMLEMKQKSLVSMGNDSEEKR 1404

  Fly   388 PIVVVSKNTQGKHMLLASGGGQHAIFLVK--ADKQDQKEN----VPVKVSGSSSISKKDKTPPQD 446
            .:.....|.:.    ||....|.::.|:|  ...:..|||    |||        .:.|:..|.|
  Rat  1405 GLETAEVNPEN----LAKECIQKSLLLLKFLPMSKSSKENCDKLVPV--------DETDRLQPLD 1457

  Fly   447 NVDKEAENVDKQEQKENLPAKASTSSKKNKTPPQDNADK-------EAENVDKQEQKENLPAKAS 504
            ...:.:..|::..|....|.:|:|.:..:|:|..:...|       .|..|...|:    |:..|
  Rat  1458 RRQRTSSVVEEHFQGSASPTEAATPAADDKSPGLEMQPKLLPSSGPSAAEVSTAEE----PSSPS 1518

  Fly   505 TSSKKIKTPPQDDAAEEV-----EEESAQEPTPKKAKKPAAK 541
            |.:::   ||.......:     .||:...||.|: |.|..|
  Rat  1519 TPTRR---PPFTRGRLRLLSFRSMEETRPVPTVKE-KYPVLK 1556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rcc1	NP_523943.1	RCC1	42..89	CDD:278826
		RCC1	92..141	CDD:278826
		RCC1_2	131..158	CDD:290274
		RCC1	144..193	CDD:278826
		RCC1_2	182..209	CDD:290274
		RCC1	363..414	CDD:278826	9/60 (15%)
Zzef1	XP_006246919.1	EFh	<94..141	CDD:238008
		APC10-ZZEF1	250..380	CDD:176488
		CUB	<1119..1189	CDD:294042
		ZZ_EF	1779..1826	CDD:239083
		ZZ	1828..1875	CDD:239069
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900