Protein Alignment Rcc1 and Hectd4

DIOPT Version :9

• Sequence 1: NP_523943.1
• Gene: Rcc1 / 38669
• FlyBaseID: FBgn0002638
• Length: 547
• Species: Drosophila melanogaster
• Sequence 2: XP_006530414.1
• Gene: Hectd4 / 269700
• MGIID: 3647820
• Length: 4525
• Species: Mus musculus
• Alignment Length: 657
• Identity: 121/657 - (18%)
• Similarity: 194/657 - (29%)
• Gaps: 261/657 - (39%)

  Fly     1 MPRRKALTNNNNAGEAEQQPPKAKRA--------------RIAFHLELPKRRTVLGNVLVCGNGD 51
            |.|.||.::|      ::|..:|..|              .:.||..|    |:|..:......|
Mouse  3425 MKREKASSSN------KRQSSRASDADSTVLSIGGSKPEDMLWFHRAL----TLLIILRHLTKKD 3479

  Fly    52 VGQLGLGEDIL-----------ERKRLSPVAGIPDAVD--ISAGGMHNLVLTKSGDIYSFGCNDE 103
            ...||:..|.:           ...||..::|||..:|  :..|.:..            .||..
Mouse  3480 PQGLGVTSDAIADACQALVGPTAHSRLLVISGIPTHLDEAVVRGAIRK------------ACNAH 3532

  Fly   104 GALGRD----TSEDGSESKPDLIDLPGKALCISAGDSHSACLLEDGRVFAWGSFRDSHGNMGLTI 164
            |.:.:|    ..:|....||     ..||   ...||.    :|..::..:.|
Mouse  3533 GGVFKDEIYIPLQDEDPKKP-----KDKA---EGSDSK----VESEKLLGFPS------------ 3573

  Fly   165 DGNKRTPIDLMEGTVCCSIASGADHLVILTTAGKVFTVGCAEQGQLGRLSERSISGEGRRGKRDL 229
                   :|.:||:...|:|
Mouse  3574 -------VDSLEGSTSSSLA--------------------------------------------- 3586

  Fly   230 LRPTQLIITRAKPFEAIWATNYCTFMRESQTQVIWATGLNNFKQLAHETKGKEFALTPIKTELKD 294
              |...|...|...:|...::.|.    |||    |:.|:    :.....|.|..:.|:..|
Mouse  3587 --PAMSISASASTSQASVCSSQCV----SQT----ASDLS----VDPLPSGLELPVPPVLLE--- 3634

  Fly   295 IRHIAGGQHHTVILTTDLK-CSVVGRPEYGRLG-------LGDVKDVVEKPTIVKKLTEKIVSVG 351
             .|:...|.     :.|:. ||.......|.||       ...|.||....|:....|:.:.:
Mouse  3635 -PHVVSSQE-----SLDISLCSTGSLGSLGSLGEPLDNPETASVSDVGSMYTVTSLDTQPLAT-- 3691

  Fly   352 CGEVCSYAVT----------IDGKLYSWGSGVNNQLGVG----DGDDEL-----EPIVVVS---- 393
             ..:..:||.          |...|::     ||.| :|    ||:|||     |.|:.||
Mouse  3692 -RPIKGFAVVEIRSRAKIEKIRASLFN-----NNDL-IGLSSLDGEDELMEMSTEEILTVSVVNQ 3749

  Fly   394 -----------------KNTQGKHMLLASGGGQHAIFLVKADKQDQKENVPVKVSGSSSI--SKK 439
                             |:.:|:.::..:......||...|..:......|.|....|.|  ||:
Mouse  3750 SLFDTQGSPGLEDYFSDKSIKGEKLVPGAREVLTEIFKSCAHSEQTLSLTPAKPIRVSDIYLSKE 3814

  Fly   440 ---DKTP-------------------------------PQDNVDKEAENVDKQEQKENLPAK-AS 469
               .:||                               |:..:||...:   :..||..|.| .|
Mouse  3815 QINSQTPGNLLHLFFTNVRPPKKVLEDQLTQILRKYGVPKPKLDKSKYS---KAGKEQHPVKVVS 3876

  Fly   470 TSSKKNKTPPQDNADKEAENVDKQEQKENLPAKASTSSKKIKTPPQDDAAEEVEEESAQEPTPKK 534
            |.....|.|.:|.|...:            .::.:.|.||....|:.....:.:|:..::...||
Mouse  3877 TKRPVTKPPAKDKAVLSS------------LSRTALSEKKPTVKPKSPEKSKPDEKDPEKSPTKK 3929

  Fly   535 AKKPAAK 541
            .:.|..|
Mouse  3930 QEVPEEK 3936

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rcc1	NP_523943.1	RCC1	42..89	CDD:278826	11/59 (19%)
		RCC1	92..141	CDD:278826	11/52 (21%)
		RCC1_2	131..158	CDD:290274	4/26 (15%)
		RCC1	144..193	CDD:278826	6/48 (13%)
		RCC1_2	182..209	CDD:290274	2/26 (8%)
		RCC1	363..414	CDD:278826	17/80 (21%)
Hectd4	XP_006530414.1	CCDC154	149..>233	CDD:373856
		SPRY_HECT_like	2507..2662	CDD:293970
		HECTc	4127..4520	CDD:391658

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900