Protein Alignment Rcc1 and Eea1

DIOPT Version :10

• Sequence 1: NP_523943.1
• Gene: Rcc1 / 38669
• FlyBaseID: FBgn0002638
• Length: 547
• Species: Drosophila melanogaster
• Sequence 2: XP_006513585.1
• Gene: Eea1 / 216238
• MGIID: 2442192
• Length: 1458
• Species: Mus musculus
• Alignment Length: 316
• Identity: 67/316 - (21%)
• Similarity: 126/316 - (39%)
• Gaps: 72/316 - (22%)

  Fly   257 ESQTQVIWATGLNNFKQLAHETKGKEFALTPIKTELKDIRHIAGGQHHTVILTTDLKCSVVGRPE 321
            :.|.|:.....|.| .:|:.|.:.:|..::..|.:|::...|......|  ||...:.:||.:.|
Mouse   801 QQQRQLSTDLELRN-AELSRELQEQEEVVSCTKLDLQNKSEILENIKQT--LTKKEEENVVLKQE 862

  Fly   322 YGRLG---------LGD-VKDVVEKPTIVKKLTEKIVSVGCGEVCSYAVTIDGKLYSWGSGVNNQ 376
            :.:|.         ||| ::..|.:.|.||...:.:::    |:.    |...||    |.|::.
Mouse   863 FEKLSQDSKTQHKELGDRMQAAVTELTAVKAQKDALLA----ELS----TTKEKL----SKVSDS 915

  Fly   377 LGVGDGDDELEPIVVVSKNTQGKHMLLASGGGQHAIFLVKADKQDQKENVPVKVSGS-------- 433
            |.....:.|.|       |.:||..:|.         |.||.| :.|..:.|:...:
Mouse   916 LKNSKSEFEKE-------NQKGKAAVLD---------LEKACK-ELKHQLQVQAESALKEQEDLK 963

  Fly   434 SSISKKDKTPPQDNVD--------KEAENVDKQEQKENLPAKASTSSKKNKTPPQDNADKEAENV 490
            .|:.|:.:|..|..::        .:|:|..||::|:....:.:.:..|          :.||..
Mouse   964 KSLEKEKETSQQLKIELNSVKGEVSQAQNTLKQKEKDEQQLQGTINQLK----------QSAEQK 1018

  Fly   491 DKQEQKENLPAKASTSSKKIKTPPQDDAAEEVEEESAQEPTPKKAKKPAAKRGGKK 546
            .||.:......|.:.|.|.:    .::..::...::|||...:|.|..|.:...:|
Mouse  1019 KKQIEALQGEVKNAVSQKTV----LENKLQQQSSQAAQELAAEKGKLSALQSNYEK 1070

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rcc1	NP_523943.1	ATS1	42..389	CDD:444065	33/141 (23%)
		Borrelia_P83	<419..>508	CDD:114011	19/104 (18%)
Eea1	XP_006513585.1	SMC_prok_B	126..784	CDD:274008
		SMC_prok_B	547..1381	CDD:274008	67/316 (21%)
		FYVE_EEA1	1394..1456	CDD:277269