Protein Alignment Rcc1 and Rpgr

DIOPT Version :9

• Sequence 1: NP_523943.1
• Gene: Rcc1 / 38669
• FlyBaseID: FBgn0002638
• Length: 547
• Species: Drosophila melanogaster
• Sequence 2: NP_001171421.1
• Gene: Rpgr / 19893
• MGIID: 1344037
• Length: 1039
• Species: Mus musculus
• Alignment Length: 558
• Identity: 137/558 - (24%)
• Similarity: 223/558 - (39%)
• Gaps: 142/558 - (25%)

  Fly    40 VLGN--VLVCGNGDVGQLGLGEDILERKRLSPVAGIPDAVDISA-GGMHNLVLTKSGDIYSFGCN 101
            |.||  :.:.|:.:.||||||......|.....|..|:.|.::| |..|.||.|.:|.:|:.|.|
Mouse    88 VTGNNKLYMFGSNNWGQLGLGSKAAIIKPTCIKALKPEKVKLAACGRNHTLVSTDTGGVYAAGGN 152

  Fly   102 DEGALGRDTSEDGSESKPDLIDLPGKAL-CISAGDSHSACLLEDGRVFAWGSFRDSHGNMGLTID 165
            :||.||...::|.......:...|...: .:|||.:.||.|.|||::|.||.  :|.|.:||...
Mouse   153 NEGQLGLGDTDDRDTFHQIVFFTPADTIKQLSAGANTSAALTEDGKLFMWGD--NSEGQIGLEDK 215

  Fly   166 GNKRTPIDLMEGTVCCSIASGADHLVILTTAGKVFTVGCAEQGQLGRLSERSISGEGRRGKRDLL 230
            .|...|.::..|.....|:.|..|...:|..|:::|.|..|.|:||
Mouse   216 SNVCIPHEVTVGKPISWISCGYYHSAFVTMDGELYTFGEPENGKLG------------------- 261

  Fly   231 RPTQLIITRAKPFEAIWATNYCTFMRESQTQVIWATGLNNFKQLAHETKGKEFALTPIKTELKDI 295
            .|.:|::....|...:                    |:.                       :.:
Mouse   262 LPNELLMNHRSPQRVL--------------------GIP-----------------------ERV 283

  Fly   296 RHIAGGQHHTVILTTDLKCSVVGRPEYGRLGLGDVKDVVEKPTIVKKL-TEKIVSVGCGEVCSYA 359
            ..:|.|..|||:||..: ....|..::|:||||.......:|.|:::: .:||..:.|||..:..
Mouse   284 IQVACGGGHTVVLTEKV-VYAFGLGQFGQLGLGTFLFETSEPKIIERIKDQKICHISCGENHTAL 347

  Fly   360 VTIDGKLYSWGSGVNNQLGVG--DGDDELEPIVVVSKNTQGKHMLLASGGGQHAIF----LVKAD 418
            :|..|.||::|.|.:.:||:|  :..::..| .:.|...:....|:|.||....:|    |...|
Mouse   348 MTELGLLYTFGDGRHGKLGLGMENFTNQFFP-TLCSNFLRFAVQLIACGGCHMLVFATPRLGTID 411

  Fly   419 K---QDQKENVPVKVSGSSSISKKDKTPPQDNVDKEAENVDKQEQKENLPAKAS----------T 470
            :   :|..|  |...:||.||   :...|:.::::......::.::|..|..||          |
Mouse   412 EPKFEDVYE--PYISTGSFSI---NDLSPRSSLNRSLSARLRRRERERPPCSASMVGTLPPLEGT 471

  Fly   471 SSKKN-------------------KTP-----PQD--------NADKEAEN---VDKQEQKE--- 497
            |:..:                   |:|     |.|        |.|.|.||   ||.:...|
Mouse   472 SASTSAYFYPSSPPFHLSVNNYPEKSPSESMEPLDSDYFEDKMNKDTETENSSAVDSENFGETND 536

  Fly   498 --NLPAKASTSSKK-------IKTPPQDDAAEEVEEES 526
              |:....:|||.:       |:.....|..|:|.|.:
Mouse   537 ILNMTHMMTTSSNEKLLDFSPIQKQQNQDTFEKVMEST 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rcc1	NP_523943.1	RCC1	42..89	CDD:278826	17/49 (35%)
		RCC1	92..141	CDD:278826	15/49 (31%)
		RCC1_2	131..158	CDD:290274	13/26 (50%)
		RCC1	144..193	CDD:278826	15/48 (31%)
		RCC1_2	182..209	CDD:290274	8/26 (31%)
		RCC1	363..414	CDD:278826	15/56 (27%)
Rpgr	NP_001171421.1	RCC1_2	78..104	CDD:290274	4/15 (27%)
		RCC1	93..139	CDD:278826	14/45 (31%)
		RCC1	144..193	CDD:278826	15/48 (31%)
		RCC1_2	180..209	CDD:290274	13/30 (43%)
		RCC1	196..243	CDD:278826	15/48 (31%)
		RCC1	246..296	CDD:278826	16/111 (14%)
		RCC1	301..348	CDD:278826	13/46 (28%)
		RCC1	352..398	CDD:278826	14/46 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833510
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750