Protein Alignment Rcc1 and ca

DIOPT Version :10

• Sequence 1: NP_523943.1
• Gene: Rcc1 / 38669
• FlyBaseID: FBgn0002638
• Length: 547
• Species: Drosophila melanogaster
• Sequence 2: XP_061499486.1
• Gene: ca / 1274071
• VectorBaseID: AGAMI1_011079
• Length: 2093
• Species: Anopheles gambiae
• Alignment Length: 669
• Identity: 146/669 - (21%)
• Similarity: 242/669 - (36%)
• Gaps: 150/669 - (22%)

  Fly     4 RKALTNNNNAGEAEQQPPKAKRARIAFHLELPKRRTVLG---NVLVCGNG-------DVGQLGLG 58
            |.||  ..:|..|..|||.....|   .:||.......|   .:.:..||       ::||||:|
Mosquito  1192 RTAL--QGDAIGANGQPPAVSFLR---QIELDVLAVQCGRLHTLFLTSNGLYSMGANNLGQLGIG 1251

  Fly    59 EDILERKRLSPVAGIPDAVD------ISAGGMHNLVLTKSGDIYSFGCNDEGALGRDTSEDGSES 117
            ..::  ..|.|:  :...:|      .:||..||.|:. :|.:|::|....|.||..|..|.  :
Mosquito  1252 NHVI--NALQPM--LVKTLDGKSITHFAAGQYHNAVVA-NGLLYTWGWGVFGQLGHGTVNDC--N 1309

  Fly   118 KPDLIDL--PGKALCISAGDSHSACLLE-----DGRVFAWGSFRDSHGNMGLTIDGNKRTPIDLM 175
            ||.:::.  ..|.|.|:.|.:|:..|..     ...::.:||  :.:|.:||..:......:|..
Mosquito  1310 KPKIVEFFRNKKILQIALGHAHTMVLCRGEHETHSSLYVFGS--NHYGQLGLGQEDPFGVTVDTR 1372

  Fly   176 EG-TVCCSIASGADHL--------------VILTTAGKVFTVGCAEQGQLGRLSERSISGEGRRG 225
            .| :...|:.....||              ::|||:.|::|.|.:.|........|..:.....|
Mosquito  1373 NGKSFLISLVPRKVHLNEEICVINTKLFVNLVLTTSNKLYTWGSSPQALRLATQARKRAKSSNTG 1437

  Fly   226 KRDLLRPTQLIITRAKPFEAIWATNYCTFMRESQTQVIWATGLNNFKQLAHETKGKEFAL---TP 287
            |.........|:.....:.....|........|:|:...:|...: |.....|.|:|.:.   |.
Mosquito  1438 KGGSYSKFSSILRSGSKYNGTEHTTSAAESSPSETKTPQSTEETD-KDETETTTGEESSKQEDTE 1501

  Fly   288 IKT---ELKDIRHIAGGQHHTVILTTDLKCSVVGRPEYGRLGLGDVKDVVEKPT----------- 338
            .:|   :..|....||......|:..::|.:..|.....:|..|:..|  ||.|
Mosquito  1502 RQTNTSDPSDEESAAGQSTDASIIIPEIKITDDGPAGNEKLQAGNEAD--EKATTNSGGDDAMEH 1564

  Fly   339 -----IVKKLTE-KIVSVGCGEVCSYAVTIDGKLYSWGSGVNNQLGVGDGDDE------LEPI-- 389
                 :...|.| :||.:..|......||.||.:|:||..:..|||...|.:|      ||.:
Mosquito  1565 LFPLFVDTSLVEGRIVKISSGLYHFAIVTEDGSIYTWGKNIERQLGREGGRNEVLIPTRLETVDN 1629

  Fly   390 -----------VVVSKNTQGKHMLLASGG---GQHA--IFLVKADKQDQKENVP-----VKVSGS 433
                       ::::|:    |::.|.|.   ||.|  |.|.::....:...:|     |::..|
Mosquito  1630 VEHVECGADFTLIMTKD----HVVKAWGNNNMGQCAKEINLDRSGIPGKLVRLPISNRVVRIPDS 1690

  Fly   434 SSISK---KDKTPPQDNVDKEAE-------------NVDKQEQKENLPAKAST-SSKKNKTPPQD 481
            |...:   :.|.|..|.|..:..             .|.|...::.:....|| ||..|.....:
Mosquito  1691 SQFIEAPYEVKLPTNDGVGYDESLRFLKSMPKFRRTFVLKSALEKLISNSISTISSSLNDVSNAE 1755

  Fly   482 NADK----------------EAENVDKQEQKENLPAKASTSSKKIKTPPQ----DDAAEEVEEES 526
            ..|.                :.:...:|:|:......:|..|....|.|.    ||  ||.:||.
Mosquito  1756 EVDDVVGDLPDSLGEGRLLLQQQQQQQQQQQHANSTMSSLQSVSYATSPTSLAIDD--EEDDEEE 1818

  Fly   527 AQEPTPKKAKKPAAKRGGK 545
            ..|...::|.......||:
Mosquito  1819 DDEDDDEEAGIVGECEGGR 1837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rcc1	NP_523943.1	ATS1	42..389	CDD:444065	94/413 (23%)
		Borrelia_P83	<419..>508	CDD:114011	19/126 (15%)
ca	XP_061499486.1	None