DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33523 and YKL091C

DIOPT Version :9

Sequence 1:	NP_001261457.1	Gene:	CG33523 / 38668	FlyBaseID:	FBgn0053523	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_012832.1	Gene:	YKL091C / 853771	SGDID:	S000001574	Length:	310	Species:	Saccharomyces cerevisiae

Alignment Length:	296	Identity:	68/296 - (22%)
Similarity:	113/296 - (38%)	Gaps:	70/296 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGVKVKETTPQQIEELRDRFNRKYASSPPAAPFHPTDID-------------------RIRNDHL 46
            |...:.:|.||             ..||.|.|..|.::.                   :.|.|..
Yeast     1 MTTSILDTYPQ-------------ICSPNALPGTPGNLTKEQEEALLQFRSILLEKNYKERLDDS 52

  Fly    47 WLQRFLEMYDLDMETSFNSLWETCILRQSTGANDIDESELN------QEYLKEGSV---FVHNTD 102
            .|.|||.....|:..|.....||...|:..|||.|.|...|      :|.:|...:   :.|:.|
Yeast    53 TLLRFLRARKFDINASVEMFVETERWREEYGANTIIEDYENNKEAEDKERIKLAKMYPQYYHHVD 117

  Fly   103 VDGKPL---------LVFRVKMHSKSKNLDELIR----IVVYWVER-TQREQHL--TQLTIFFDM 151
            .||:||         |....|:.::.:.|..|::    ...|.|.. ::|..:|  |..|: .|:
Yeast   118 KDGRPLYFEELGGINLKKMYKITTEKQMLRNLVKEYELFATYRVPACSRRAGYLIETSCTV-LDL 181

  Fly   152 SGTSLASM--DLEFVKRIVETFKQFYPNSLNYILVYELGWVLNAAFKVIKAVLPPKAVE---ILK 211
            .|.||::.  .|.::|.:.:..:.:||..:....:....:..:..||::|..|.|..|.   ||.
Yeast   182 KGISLSNAYHVLSYIKDVADISQNYYPERMGKFYIIHSPFGFSTMFKMVKPFLDPVTVSKIFILG 246

  Fly   212 MISKKDINQYINKDNCLAIWGG-------EDNYEFS 240
            ...||::.:.|..:|....:||       .|.:.:|
Yeast   247 SSYKKELLKQIPIENLPVKYGGTSVLHNPNDKFYYS 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33523	NP_001261457.1	CRAL_TRIO	94..234	CDD:279044	38/170 (22%)
CG33523	NP_001261457.1	Motile_Sperm	293..396	CDD:279029
YKL091C	NP_012832.1	CRAL_TRIO_N	30..75	CDD:215024	8/44 (18%)
YKL091C	NP_012832.1	SEC14	101..271	CDD:214706	40/170 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810