DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG33523 and TTPA

DIOPT Version :9

Sequence 1:NP_001261457.1 Gene:CG33523 / 38668 FlyBaseID:FBgn0053523 Length:654 Species:Drosophila melanogaster
Sequence 2:NP_000361.1 Gene:TTPA / 7274 HGNCID:12404 Length:278 Species:Homo sapiens


Alignment Length:242 Identity:55/242 - (22%)
Similarity:89/242 - (36%) Gaps:61/242 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 PAAPFHPTDIDRIRNDHLWLQRFLEMYDLDMETSFNSL-----WET-CILRQSTGANDIDESELN 87
            |.||...||        .:|.|||...|.|::.::..|     |.. |             .|::
Human    41 PLAPLPLTD--------SFLLRFLRARDFDLDLAWRLLKNYYKWRAEC-------------PEIS 84

  Fly    88 QE--------YLKEG-SVFVHNTDVDGKPLLVFRVKMHSKSK--NLDELIRI-------VVYWVE 134
            .:        .||.| ...:.:.|..|..:|::|: .|...|  ...::.|:       :|..||
Human    85 ADLHPRSIIGLLKAGYHGVLRSRDPTGSKVLIYRI-AHWDPKVFTAYDVFRVSLITSELIVQEVE 148

  Fly   135 RTQREQHLTQLTIFFDMSGTSLA---SMDLEFVKRIVETFKQFYPNSLNYILVYELGWVLNAAFK 196
             |||    ..:...||:.|...:   .:.....|:|.......:|..:..|.:.....:.:|.|.
Human   149 -TQR----NGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFS 208

  Fly   197 VIKAVLPPKAVEILKMIS---KKDINQYINKDNCLAIWGGEDNYEFS 240
            :||..|..|..|.:.|..   |:.:.|:. .|.....:|||   |||
Human   209 MIKPFLTEKIKERIHMHGNNYKQSLLQHF-PDILPLEYGGE---EFS 251

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG33523NP_001261457.1 CRAL_TRIO 94..234 CDD:279044 33/155 (21%)
Motile_Sperm 293..396 CDD:279029
TTPANP_000361.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..20
CRAL_TRIO_N <40..73 CDD:215024 12/39 (31%)
CRAL_TRIO 99..248 CDD:395525 33/155 (21%)
Phosphatidylinositol 3,4-bisphosphate binding. /evidence=ECO:0000250|UniProtKB:Q8BWP5 190..192 0/1 (0%)
Phosphatidylinositol 4,5-bisphosphate binding. /evidence=ECO:0000250|UniProtKB:Q8BWP5 208..211 0/2 (0%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1471
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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