DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33523 and Sec14l3

DIOPT Version :9

Sequence 1:	NP_001261457.1	Gene:	CG33523 / 38668	FlyBaseID:	FBgn0053523	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_072130.1	Gene:	Sec14l3 / 64543	RGDID:	620812	Length:	400	Species:	Rattus norvegicus

Alignment Length:	265	Identity:	59/265 - (22%)
Similarity:	111/265 - (41%)	Gaps:	54/265 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGVKVKETTPQQIEELRDRFNRKYASSPPAAPFHPTDIDRIRNDHLWLQRFLEMYDLDMETSFNS 65
            |..:|.:.:|:|.|.|. :|........||.| :|        |..:|.|:|...:.|::.|...
  Rat     1 MSGRVGDLSPKQAETLA-KFRENVQDVLPALP-NP--------DDYFLLRWLRARNFDLQKSEAM 55

  Fly    66 LWETCILRQSTGANDIDE------SELNQEYLKEGSVFVHNTDVDGKPL------------LVFR 112
            |.:....|::.   |||.      .|:.|:|:..|   :...|.||.||            |:|.
  Rat    56 LRKYMEFRKTM---DIDHILDWQPPEVIQKYMPGG---LCGYDRDGCPLWYDIIGPLDPKGLLFS 114

  Fly   113 VK----MHSKSKNLDELIRIVVYWVERTQREQHLTQLTIFFDMSGTSLASMDLEFVKRIVETFKQ 173
            |.    :.:|.::.:.::.......||..|:  :..:.:.||..|..|.    .|.|.:||.:::
  Rat   115 VTKQDLLKTKMRDCERILHECDLQTERLGRK--IETIVMIFDCEGLGLK----HFWKPLVEVYQE 173

  Fly   174 F-------YPNSLNYILVYELGWVLNAAFKVIKAVLPP---KAVEILKMISKKDINQYINKDNCL 228
            |       ||.:|.::|:.:...:....:.::|..|..   :.:.:|....|:.:.:.|:.:...
  Rat   174 FFGLLEENYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIVVLGNSWKEGLLKLISPEELP 238

  Fly   229 AIWGG 233
            |.:||
  Rat   239 AHFGG 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33523	NP_001261457.1	CRAL_TRIO	94..234	CDD:279044	34/166 (20%)
CG33523	NP_001261457.1	Motile_Sperm	293..396	CDD:279029
Sec14l3	NP_072130.1	CRAL_TRIO_N	13..59	CDD:215024	14/55 (25%)
Sec14l3	NP_072130.1	SEC14	76..245	CDD:214706	37/177 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810