DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33523 and mospd2

DIOPT Version :9

Sequence 1:	NP_001261457.1	Gene:	CG33523 / 38668	FlyBaseID:	FBgn0053523	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_001008142.1	Gene:	mospd2 / 493504	XenbaseID:	XB-GENE-957659	Length:	509	Species:	Xenopus tropicalis

Alignment Length:	499	Identity:	137/499 - (27%)
Similarity:	248/499 - (49%)	Gaps:	42/499 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ETTPQQIEELRDRFNRKYASSPPAAPFHPTDIDRIRNDHLWLQRFLEMYDLDMETSFNSLWETCI 71
            |...|.|:|.|.||.::|... .|..:...|::|::.|...::.:|.......|.:...:.|:..
Frog     3 EDKEQLIQETRKRFTQEYLQD-KADRYDSRDVERLQKDDTLVESYLMWRHYVTEEALKMMDESLK 66

  Fly    72 LRQSTGANDIDESELNQEYLKEGSVFVHNTDVDGKPLLVFRVKMHSK-SKNLDELIRIVVYWVER 135
            .|:..|.||::||.:.:...:.|:.::|..|.:|..||..:||:|.: .|..::..:.|.:|:||
Frog    67 WRKDIGVNDLNESTIPKWCFETGASYLHGYDKEGNKLLWLKVKLHVRDGKTTEDKKKFVAFWLER 131

  Fly   136 TQREQHLTQLTIFFDMSGTSLASMDLEFVKRIVETFKQFYPNSLNYILVYELGWVLNAAFKVIKA 200
            ..|.:....:|:.|||..:.|:::|::||:.:|.:||.:||..|:.:::||:.|:||||||::|:
Frog   132 YARREPGKFITVVFDMVDSGLSNVDMDFVRFVVNSFKTYYPRYLSKMVIYEMPWILNAAFKIVKS 196

  Fly   201 VLPPKAVEILKMISKKDINQYINKDNCLAIWGGEDNYEFSFVPEAKKVISKPVAAN---AGDDD- 261
            .|.|:|:.:||..:|..:..||:.:......||.|.:::|:.|........|:..|   |.:||
Frog   197 WLGPEAISLLKFANKNQVQDYISAEYLPPHMGGTDPFKYSYPPLPDDDFQTPLCENGPVASEDDS 261

  Fly   262 ---------------------QFADKKVTFVDSAPMVLKETNINKMHTPSEG-MLHINPKDFVNF 304
                                 ..:|.::...|.....:|:.|..|..|..:| :|||:|.:.::|
Frog   262 ESKLSESDLRDTVDLSVPKKISISDDQIKQEDVEKNDVKQKNNRKASTVFKGPLLHISPAEELHF 326

  Fly   305 NSKNA---EATMTIKSIATSAVTYKIQTTSPEKFRVRPRCGIIQPNQEATINIWLKSEHKLSDDS 366
            .||.:   :..:.:.::..:.|.:|::||:|||:||:|.....:|.  :|::|.:..........
Frog   327 GSKESGERKCVIVLNNVTKNTVAFKVRTTAPEKYRVKPSNSSCEPG--STVDIVVSLHAAFVASL 389

  Fly   367 KDKFLVMA--MVAPGGECGGADVTELWRSKSPTSADVEQHRLVCRFDENKSKAQLDCASKSSKAS 429
            :|:|||||  |..|.| ....::|:.|  |....:.|.:|||.|...|....|.|...|.:...|
Frog   390 QDRFLVMAAEMEQPSG-ASTQELTQFW--KEVPRSKVMEHRLRCHVVETSKPASLILKSNTMNHS 451

  Fly   430 V----DCSKKSGAGVDPATAMERQLAFTQNLQYVTLALLFLLFA 469
            |    |...|....::....:|.|:......|::...||.:|.|
Frog   452 VSDSDDLHFKLNQLLETNRRLEAQMGHCLWFQHMLATLLSILVA 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33523	NP_001261457.1	CRAL_TRIO	94..234	CDD:279044	48/140 (34%)
CG33523	NP_001261457.1	Motile_Sperm	293..396	CDD:279029	32/107 (30%)
mospd2	NP_001008142.1	CRAL_TRIO	88..230	CDD:366224	48/141 (34%)
mospd2	NP_001008142.1	Motile_Sperm	315..419	CDD:334183	32/108 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	110	1.000	Domainoid score	I6224
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H22125
Inparanoid	1	1.050	196	1.000	Inparanoid score	I3707
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D217631at33208
OrthoFinder	1	1.000	-	-		FOG0002427
OrthoInspector	1	1.000	-	-		otm47773
Panther	1	1.100	-	-	LDO	PTHR46384
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1928
SonicParanoid	1	1.000	-	-		X5431
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.190