DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33523 and sec14l5

DIOPT Version :9

Sequence 1:	NP_001261457.1	Gene:	CG33523 / 38668	FlyBaseID:	FBgn0053523	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	XP_031749906.1	Gene:	sec14l5 / 493292	XenbaseID:	XB-GENE-953433	Length:	793	Species:	Xenopus tropicalis

Alignment Length:	286	Identity:	62/286 - (21%)
Similarity:	109/286 - (38%)	Gaps:	69/286 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 SSPPAA--PFHPTDIDRIRNDHL--------------------WLQ--------------RFLEM 54
            |||.||  ....|..|::..|::                    |||              |||..
Frog   222 SSPTAATHELSSTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKGKIPKDEHILRFLRA 286

  Fly    55 YDLDMETSFNSLWETCILRQSTGANDI----DESELNQEYLKEGSVFVHNTDVDGKPLLVFRV-K 114
            .|.:::.:...|.::...|:....:.:    |..::..:|...|   .|:.|.||:||.|.|: :
Frog   287 RDFNIDKAREILCQSLTWRKQHHVDYLLSTWDPPQVLHDYYAGG---WHHHDRDGRPLYVLRLGQ 348

  Fly   115 MHSKS--KNLDE--LIRIVVYWVERTQRE---------QHLTQLTIFFDMSGTSLASMDLEFVK- 165
            |.:|.  :.|.|  |:|.|:...|...|.         :.::..|...|:.|.::..:....||
Frog   349 MDTKGLVRALGEESLLRHVLSINEEGLRRCEENTNIFGRPISSWTCLVDLEGLNMRHLWRPGVKA 413

  Fly   166 --RIVETFKQFYPNSLNYILVYELGWVLNAAFKVIKAVLPPKAVEILKMISKKD------INQYI 222
              ||:|..:..||.:|..:|:.....|....:.::...:.....:...:.:..|      :..||
Frog   414 LLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDENTRKKFLIYAGNDYQGPGGLIDYI 478

  Fly   223 NKDNCLAIWGGEDNYEFS---FVPEA 245
            :|:......|||...|.|   .||:|
Frog   479 DKEVIPDFLGGECMCEVSEGGMVPKA 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33523	NP_001261457.1	CRAL_TRIO	94..234	CDD:279044	36/162 (22%)
CG33523	NP_001261457.1	Motile_Sperm	293..396	CDD:279029
sec14l5	XP_031749906.1	PRELI	17..173	CDD:398400
		CRAL_TRIO_N	256..301	CDD:215024	8/44 (18%)
		CRAL_TRIO	326..490	CDD:395525	37/166 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910