DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33523 and mospd2

DIOPT Version :9

Sequence 1:	NP_001261457.1	Gene:	CG33523 / 38668	FlyBaseID:	FBgn0053523	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_001007294.2	Gene:	mospd2 / 492327	ZFINID:	ZDB-GENE-041114-1	Length:	526	Species:	Danio rerio

Alignment Length:	507	Identity:	128/507 - (25%)
Similarity:	240/507 - (47%)	Gaps:	52/507 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 QIEELRDRFNRKYASSPPA-APFHPTDIDRIRNDHLWLQRFLEMYDLDMETSFNSLWETCILRQS 75
            :|:|.|.||..:|..:..: ..:...|::::..|...::.:|......:|.:...:.|:...|:.
Zfish    16 KIQETRQRFKSEYVEAQESQEKYDSRDVEKLFRDDALVEGYLTWRHFIVEDTLKMIDESLQWRRE 80

  Fly    76 TGANDIDESELNQEYLKEGSVFVHNTDVDGKPLLVFRVKMHSKS-KNLDELIRIVVYWVERTQRE 139
            ...||:.||.:.:...:.|:|::|..|.:|..|..|:||:|.|. |.:.:..|.|.:|:||..:.
Zfish    81 FSVNDLTESSIPRWMFEIGAVYLHGYDKEGNKLFWFKVKLHIKDPKTVLDKKRYVAFWLERYAKR 145

  Fly   140 QHLTQLTIFFDMSGTSLASMDLEFVKRIVETFKQFYPNSLNYILVYELGWVLNAAFKVIKAVLPP 204
            :....||:.||||.:.|:::|::|||.|:..||.:||..|:.:::||:.|::|||:|::|..|.|
Zfish   146 EPGMPLTVVFDMSESGLSNIDMDFVKYIISCFKVYYPKFLSKMIMYEMPWIMNAAWKIVKTWLGP 210

  Fly   205 KAVEILKMISKKDINQYINKDNCLAIWGGEDNYEFSFVPEAKKVISKPVAANA------------ 257
            .|:..||.:||.||..::..::.....||.|.:::|:.|........|:..|.
Zfish   211 DAISKLKFVSKSDIQTFVGPEHLPPYMGGTDQFKYSYPPLPDDDFQSPICENGPIISEDESDLKD 275

  Fly   258 -------------GDDDQFADKKVTFVD-----SAPMVLKETNINKMHTPS----EGMLHINPKD 300
                         ..|.....|||.|:.     |..:..:...:.....|:    ..::||:|.:
Zfish   276 AESESKETLESSFNTDQSIKPKKVNFMTEDGQRSEELDRESVRLKGARKPTTTFKATLMHISPAE 340

  Fly   301 FVNFNSKNAE--ATMTIKSIATSAVTYKIQTTSPEKFRVRPRCGIIQPNQEATINIWLKSEHKLS 363
            .::|.:..:|  ..:.:.::..:.|.:|::||:|||:||:|.....:|.  |:::|.:.......
Zfish   341 ELSFGASESEKKCLIVLNNVTKNHVAFKVRTTAPEKYRVKPSNSSCEPG--ASVDIVVSLHGGFQ 403

  Fly   364 DDSKDKFLVMA--MVAPGGECGGADVTELWRSKSPTSADVEQHRLVCRFDENKSKAQLDCASKSS 426
            ...:|:|||||  |.:..| ....|:.:.|  |..:...:.:|||.|...|:......:.....|
Zfish   404 ASPQDRFLVMAAEMESSSG-AAATDLAQFW--KEVSKPKIMEHRLRCHVLESPKSILSNSFEFPS 465

  Fly   427 KASVDCSKKSGAG------VDPATAMERQLAFTQNLQYVTLALL-FLLFAGF 471
            ..:.:.::.....      :....|:|::|.:....|.|.|.|| |||...|
Zfish   466 SPTTNVNEHQDLQSTLMRLLATNAALEQKLDWCLWTQKVLLLLLSFLLALSF 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33523	NP_001261457.1	CRAL_TRIO	94..234	CDD:279044	52/140 (37%)
CG33523	NP_001261457.1	Motile_Sperm	293..396	CDD:279029	29/106 (27%)
mospd2	NP_001007294.2	CRAL_TRIO	99..240	CDD:279044	52/140 (37%)
mospd2	NP_001007294.2	Motile_Sperm	333..437	CDD:279029	29/108 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581552
Domainoid	1	1.000	114	1.000	Domainoid score	I6035
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22125
Inparanoid	1	1.050	185	1.000	Inparanoid score	I3935
OMA	1	1.010	-	-		QHG49365
OrthoDB	1	1.010	-	-		D217631at33208
OrthoFinder	1	1.000	-	-		FOG0002427
OrthoInspector	1	1.000	-	-		otm26349
orthoMCL	1	0.900	-	-		OOG6_101230
Panther	1	1.100	-	-	LDO	PTHR46384
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5431
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910