DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33523 and Mospd2

DIOPT Version :9

Sequence 1:	NP_001261457.1	Gene:	CG33523 / 38668	FlyBaseID:	FBgn0053523	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	XP_006256927.1	Gene:	Mospd2 / 363463	RGDID:	1563952	Length:	518	Species:	Rattus norvegicus

Alignment Length:	518	Identity:	139/518 - (26%)
Similarity:	253/518 - (48%)	Gaps:	67/518 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 IEELRDRFNRKYASSPPAAPFHPTDIDRIRNDHLWLQRFLEMYDLDMETSFNSLWETCILRQSTG 77
            |.|.|.||..:|.:. .:..:.|.|::|::.|..|::.:|......::.:...|.|:...|:...
  Rat    13 ISETRRRFEAEYVTE-KSEKYDPRDVERLQQDDNWVESYLHWRHNVVDETLKMLDESFQWRKELS 76

  Fly    78 ANDIDESELNQEYLKEGSVFVHNTDVDGKPLLVFRVKMHSK-SKNLDELIRIVVYWVERTQREQH 141
            .||:.||.:.:..|:.|.:::|..|.:|..|...|||.|.| .|.:.:..:::.:|:||..:.::
  Rat    77 VNDLSESSIPRWLLELGGIYLHGYDKEGNKLFWIRVKYHIKDQKTIMDKKKLIAFWLERYAKREN 141

  Fly   142 LTQLTIFFDMSGTSLASMDLEFVKRIVETFKQFYPNSLNYILVYELGWVLNAAFKVIKAVLPPKA 206
            ...:|:.||||.|.|.|:|::||:.|:..||.:||..|:.|:::::.|::|||||::|:.|.|:|
  Rat   142 GKPITVMFDMSETGLNSIDMDFVRFIINCFKVYYPKYLSKIVIFDMPWIMNAAFKIVKSWLGPEA 206

  Fly   207 VEILKMISKKDINQYINKDNCLAIWGGEDNYEFSFVPEAKKVISKPVAANA--GDDDQFADKKVT 269
            |.:||..||.:|.:|::.:......||.|.:::|:.|........|:..|.  ..:|:.:.|:..
  Rat   207 VSLLKFTSKNEIQEYVSVEYLPPHMGGTDPFKYSYPPLVDDDFQTPLCENGPIASEDETSSKEDI 271

  Fly   270 FVDSAPMVLKET--NINKMHTPSEG-----------------------------------MLHIN 297
            ..|.     |||  .|:....|::.                                   :|||:
  Rat   272 EGDG-----KETLETISNEEQPAQSEKSNPTESASKRDENEKVDSKTKPFKKPLSVFKGPLLHIS 331

  Fly   298 PKD---FVNFNSKNAEATMTIKSIATSAVTYKIQTTSPEKFRVRPRCGIIQPNQEATINIWLKSE 359
            |.:   |.:..|...:..:.:.::..:.|.:|::||:|||:||:|......|.  |:::|.:...
  Rat   332 PAEELYFGSIESGEKKTLIVLTNVTKNIVAFKVRTTAPEKYRVKPSNSSCDPG--ASVDIIVSPH 394

  Fly   360 HKLSDDSKDKFLVMA--MVAPGGECGGADVTELWRSKSPTSADVEQHRLVCRFDENKSKAQL--- 419
            ..|:..::|:||:||  |....| .|.|::|:.|  |....:.|.:|||.|...|:.....|
  Rat   395 GGLTVSAQDRFLIMAAEMEQSSG-TGPAELTQFW--KEVPRSKVMEHRLRCHTVESSKPNSLMLK 456

  Fly   420 -DCASKSSKASVDCSKKSGAGVDPATAMERQLA----FTQNLQYVTLALLFLLF-AGFGFLMY 476
             ..::.|.|.|.|...:....::....:|.||.    |.|.|  :||.::.|.| ..|.:.:|
  Rat   457 DSVSALSDKTSEDLYLQLNRLLESNRKLEDQLQRSIWFQQLL--LTLTMVLLAFVVSFFYSLY 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33523	NP_001261457.1	CRAL_TRIO	94..234	CDD:279044	50/140 (36%)
CG33523	NP_001261457.1	Motile_Sperm	293..396	CDD:279029	32/107 (30%)
Mospd2	XP_006256927.1	CRAL_TRIO	93..234	CDD:279044	50/140 (36%)
Mospd2	XP_006256927.1	Motile_Sperm	327..431	CDD:279029	32/108 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341547
Domainoid	1	1.000	114	1.000	Domainoid score	I5914
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22125
Inparanoid	1	1.050	198	1.000	Inparanoid score	I3724
OMA	1	1.010	-	-		QHG49365
OrthoDB	1	1.010	-	-		D217631at33208
OrthoFinder	1	1.000	-	-		FOG0002427
OrthoInspector	1	1.000	-	-		otm44739
orthoMCL	1	0.900	-	-		OOG6_101230
Panther	1	1.100	-	-	LDO	PTHR46384
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5431
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.910