DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33523 and Sec14l1

DIOPT Version :9

Sequence 1:	NP_001261457.1	Gene:	CG33523 / 38668	FlyBaseID:	FBgn0053523	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_001101779.1	Gene:	Sec14l1 / 360668	RGDID:	1563123	Length:	720	Species:	Rattus norvegicus

Alignment Length:	466	Identity:	88/466 - (18%)
Similarity:	173/466 - (37%)	Gaps:	141/466 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 TPQQIEELRDRFNRKYASSPPAAPFHPTDIDRIRNDHLWLQ--------------RFLEMYDLDM 59
            ||.  ::|...:.::|...  ..|...:.:.|:|.   |||              |||...|.::
  Rat   235 TPD--DKLDADYIKRYLGD--LTPLQESCLIRLRQ---WLQETHKGKIPKDEHILRFLRARDFNI 292

  Fly    60 ETSFNSLWETCILRQSTGANDIDES----ELNQEYLKEGSVFVHNTDVDGKPLLVFRV-KMHSKS 119
            :.:...:.::...|:....:.|.::    ::.|:|...|   .|:.|.||:||.|.|: :|.:|.
  Rat   293 DKAREIMCQSLTWRKQHQVDYILDTWTPPQVLQDYYAGG---WHHHDKDGRPLYVLRLGQMDTKG 354

  Fly   120 --KNLDE--LIRIVVYWVERTQRE---------QHLTQLTIFFDMSGTSLASMDLEFVK---RIV 168
              :.|.|  |:|.|:...|...|.         :.::..|...|:.|.::..:....||   ||:
  Rat   355 LVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRII 419

  Fly   169 ETFKQFYPNSLNYILVYELGWVLNAAFKVIKAVLPPKAVEILKMISKKDINQYINKDNCLAIWGG 233
            |..:..||.:|..:|             :::|   |:...:|..:    ::.:|
  Rat   420 EVVEANYPETLGRLL-------------ILRA---PRVFPVLWTL----VSPFI----------- 453

  Fly   234 EDNYEFSFVPEAKKVISKPVAANAGDDDQ-------FADKKV--TFVDSAPMVLKETNINKMHTP 289
            :||....|:            ..||:|.|       :.||::  .|:....|         ...|
  Rat   454 DDNTRRKFL------------IYAGNDYQGPGGLLDYIDKEIIPDFLSGECM---------CDVP 497

  Fly   290 SEGM----LHINPKDFVNFNSKNAEATMTIKSIATSAVTYKIQTTSPEKFRVRPRCGIIQPNQEA 350
            ..|:    |:..|::.     :|.:..:..::|..||..:|   .:|.:.       :||....|
  Rat   498 EGGLVPKSLYRTPEEL-----ENEDLKLWTETIYQSASVFK---GAPHEI-------LIQIVDAA 547

  Fly   351 TINIW-------------LKSEHKLSDDSKDKFLVMAMVAPGGECGGADVTELWRSKSPTSADVE 402
            ::..|             ..|:.......||.....::.:|||. ....:.::|:.....|  :.
  Rat   548 SVITWDFDVCKGDIVFNIYHSKRSPQPPKKDSLGAHSITSPGGN-NVQLIDKVWQLGRDYS--MV 609

  Fly   403 QHRLVCRFDEN 413
            :..|:|:..|:
  Rat   610 ESPLICKEGES 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33523	NP_001261457.1	CRAL_TRIO	94..234	CDD:279044	34/156 (22%)
CG33523	NP_001261457.1	Motile_Sperm	293..396	CDD:279029	19/119 (16%)
Sec14l1	NP_001101779.1	PRELI	17..173	CDD:282550
		CRAL_TRIO_N	257..302	CDD:215024	9/47 (19%)
		CRAL_TRIO	327..491	CDD:279044	45/209 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810