DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33523 and Ttpa

DIOPT Version :9

Sequence 1:	NP_001261457.1	Gene:	CG33523 / 38668	FlyBaseID:	FBgn0053523	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_037180.1	Gene:	Ttpa / 25571	RGDID:	3915	Length:	278	Species:	Rattus norvegicus

Alignment Length:	206	Identity:	43/206 - (20%)
Similarity:	73/206 - (35%)	Gaps:	75/206 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 IEELRDRFNRKYASSPPAAPFHPTDIDRIRNDHLWLQRFLEMYDLDMETSFNSL-----WET-CI 71
            :.|||   .|......|..|...||        .:|.|||...|.|::.::..:     |.. |
  Rat    28 LAELR---RRAQEEGVPETPQPLTD--------AFLLRFLRARDFDLDLAWRLMKNYYKWRAEC- 80

  Fly    72 LRQSTGANDIDESELNQE--------YLKEG-SVFVHNTDVDGKPLLVFRVKMHSKSKNLDELIR 127
                        .||:.:        .||.| ...:.:.|..|..:|::|:.
  Rat    81 ------------PELSADLHPRSILGLLKAGYHGVLRSRDPTGSRVLIYRIS------------- 120

  Fly   128 IVVYWVERTQREQHLTQLTIF--FDMSGTSLASMDLEFVKRIVETFKQFYPNSLNYILVYELGWV 190
               ||..:           :|  :|:...||.:.:|  :.:.|||.:    |.:..|...| ||.
  Rat   121 ---YWDPK-----------VFTAYDVFRVSLITSEL--IVQEVETQR----NGVKAIFDLE-GWQ 164

  Fly   191 LNAAFKVIKAV 201
            ::.||::..:|
  Rat   165 ISHAFQITPSV 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33523	NP_001261457.1	CRAL_TRIO	94..234	CDD:279044	23/111 (21%)
CG33523	NP_001261457.1	Motile_Sperm	293..396	CDD:279029
Ttpa	NP_037180.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
		CRAL_TRIO_N	25..73	CDD:215024	14/55 (25%)
		CRAL_TRIO	99..248	CDD:395525	23/111 (21%)
		Phosphatidylinositol 3,4-bisphosphate binding. /evidence=ECO:0000250\|UniProtKB:Q8BWP5	190..192
		Phosphatidylinositol 4,5-bisphosphate binding. /evidence=ECO:0000250\|UniProtKB:Q8BWP5	208..211
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900