Protein Alignment CG33523 and SEC14L2

DIOPT Version :9

• Sequence 1: NP_001261457.1
• Gene: CG33523 / 38668
• FlyBaseID: FBgn0053523
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_036561.1
• Gene: SEC14L2 / 23541
• HGNCID: 10699
• Length: 403
• Species: Homo sapiens
• Alignment Length: 412
• Identity: 80/412 - (19%)
• Similarity: 150/412 - (36%)
• Gaps: 102/412 - (24%)

  Fly     1 MGVKVKETTPQQIEELRDRFNRKYASSPPAAPFHPTDIDRIRNDHLWLQRFLEMYDLDMETSFNS 65
            |..:|.:.:|:|.|.|. :|........||.| :|        |..:|.|:|.....|::.|...
Human     1 MSGRVGDLSPRQKEALA-KFRENVQDVLPALP-NP--------DDYFLLRWLRARSFDLQKSEAM 55

  Fly    66 LWETCILRQSTGANDIDE------SELNQEYLKEGSVFVHNTDVDGKPL------------LVFR 112
            |.:....|:.   .|||.      .|:.|:||..|   :...|:||.|:            |:|.
Human    56 LRKHVEFRKQ---KDIDNIISWQPPEVIQQYLSGG---MCGYDLDGCPVWYDIIGPLDAKGLLFS 114

  Fly   113 VK----MHSKSKNLDELIRIVVYWVERTQREQHLTQLTIFFDMSGTSLASMDLEFVKRIVETFKQ 173
            ..    :.:|.:..:.|::...:  :.|:..:.:..:||.:|..|..|..:    .|..||.:.:
Human   115 ASKQDLLRTKMRECELLLQECAH--QTTKLGRKVETITIIYDCEGLGLKHL----WKPAVEAYGE 173

  Fly   174 F-------YPNSLNYILVYELGWVLNAAFKVIKAVLPP---KAVEILKMISKKDINQYINKDNCL 228
            |       ||.:|..:.|.:...:...|:.:||..|..   |.:.:|....|:.:.::|:.|...
Human   174 FLCMFEENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVP 238

  Fly   229 AIWGG-------------EDNY------EFSFVPEAKKVISKPVAANAGDDDQFADKKVTF---- 270
            ..:||             :.||      ::....:.|:.....|..:.|...| .:.::.|
Human   239 VEYGGTMTDPDGNPKCKSKINYGGDIPRKYYVRDQVKQQYEHSVQISRGSSHQ-VEYEILFPGCV 302

  Fly   271 ------VDSAPM---VLKETNINKMHTPSEGMLHINPKDFVNFNSKNAEATMTIKS--------- 317
                  .|.|.:   :..:|.:.:.....| |..:.|....|.:....:.|:|...
Human   303 LRWQFMSDGADVGFGIFLKTKMGERQRAGE-MTEVLPNQRYNSHLVPEDGTLTCSDPGIYVLRFD 366

  Fly   318 -----IATSAVTYKIQTTSPEK 334
                 |....|.:.::...|:|
Human   367 NTYSFIHAKKVNFTVEVLLPDK 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33523	NP_001261457.1	CRAL_TRIO	94..234	CDD:279044	34/178 (19%)
		Motile_Sperm	293..396	CDD:279029	9/56 (16%)
SEC14L2	NP_036561.1	CRAL_TRIO_N	13..59	CDD:215024	14/55 (25%)
		SEC14	76..244	CDD:214706	37/176 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810