DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32407 and SEC14L5

DIOPT Version :9

Sequence 1:	NP_001261456.1	Gene:	CG32407 / 38667	FlyBaseID:	FBgn0052407	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_055507.1	Gene:	SEC14L5 / 9717	HGNCID:	29032	Length:	696	Species:	Homo sapiens

Alignment Length:	179	Identity:	46/179 - (25%)
Similarity:	78/179 - (43%)	Gaps:	24/179 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 DLWITKLLQVYDFDVEKCITRLWDNLAWRKSFGVYDITEA----NLNQEFLNDGSIYVHNKDRDG 104
            |..|.:.|:.:||.::|....|..:|:|||...|..:.:.    .|.:||...|   .|.:|.||
Human   264 DEHILRFLRAHDFHLDKAREMLRQSLSWRKQHQVDLLLQTWQPPALLEEFYAGG---WHYQDIDG 325

  Fly   105 KPLLILTI-----KKHSKSRNQEDLLRILVFWIERLQRDSN---------LDKITIFMDMTGAGL 155
            :||.||.:     |...|:..:|.|||.::...|..|:...         :...|..:|:.|..:
Human   326 RPLYILRLGQMDTKGLMKAVGEEALLRHVLSVNEEGQKRCEGSTRQLGRPISSWTCLLDLEGLNM 390

  Fly   156 SNLDMGFIKSI---IGVFETKYPYVPNYILVHDLPFLLDAAFKLVKTFL 201
            .:|....:|::   |.|.|..||.....:|:...|.:....:.|:..|:
Human   391 RHLWRPGVKALLRMIEVVEDNYPETLGRLLIVRAPRVFPVLWTLISPFI 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32407	NP_001261456.1	CRAL_TRIO	92..233	CDD:279044	31/127 (24%)
SEC14L5	NP_055507.1	PRELI	17..173	CDD:309720
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	178..214
		CRAL_TRIO_N	243..288	CDD:215024	7/23 (30%)
		SEC14	306..479	CDD:214706	34/137 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820