DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32407 and Clvs1

DIOPT Version :9

Sequence 1:	NP_001261456.1	Gene:	CG32407 / 38667	FlyBaseID:	FBgn0052407	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_001342112.1	Gene:	Clvs1 / 74438	MGIID:	1921688	Length:	354	Species:	Mus musculus

Alignment Length:	245	Identity:	52/245 - (21%)
Similarity:	97/245 - (39%)	Gaps:	50/245 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PTPEQISQ-----VKTSILQ-----------RLEKEPPAEPFHPNDLKRITD------------- 42
            |:|:.:|.     .|.:.||           |||.....:..| .|::::.|
Mouse     8 PSPQSLSTWEGDLAKMTHLQAGLSPDTIEKARLELNENPDILH-QDIQQVRDMIITRPDIGFLRT 71

  Fly    43 SDLWITKLLQVYDF---DVEKCITRLWD----NLAWRKSFGVYDITEANLNQEFLNDGSIYVHNK 100
            .|.:|.:.|:...|   |..:.:.:.:.    ||...|:|...|   ..:.:..::.....:.|:
Mouse    72 DDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFKNFKADD---PGIKRALIDGFPGVLENR 133

  Fly   101 DRDGKPLLILTIKKHSKSRNQ-EDLLRILVFWIERLQRDSNL--DKITIFMDMTGAGL---SNLD 159
            |..|:.:|:|......:|||. .|:||.::..:|.|..|..|  :...:.:|.:....   |.|.
Mouse   134 DHYGRKILLLFAANWDQSRNSFTDILRAILLSLEVLIEDPELQINGFILIIDWSNFSFKQASKLT 198

  Fly   160 MGFIKSIIGVFETKYPYVPNYILVH--DLPFLLDAAFKLVKTFLPPEALK 207
            ...:|..|...:..:|  ..:..||  :.|:.:.|.:.|:|.||..:..|
Mouse   199 PSILKLAIEGLQDSFP--ARFGGVHFVNQPWYIHALYTLIKPFLKDKTRK 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32407	NP_001261456.1	CRAL_TRIO	92..233	CDD:279044	30/124 (24%)
Clvs1	NP_001342112.1	CRAL_TRIO_N	51..97	CDD:215024	7/45 (16%)
		CRAL_TRIO	125..274	CDD:366224	30/124 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	317..354
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810