DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32407 and Sec14l1

DIOPT Version :9

Sequence 1:	NP_001261456.1	Gene:	CG32407 / 38667	FlyBaseID:	FBgn0052407	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_083053.2	Gene:	Sec14l1 / 74136	MGIID:	1921386	Length:	719	Species:	Mus musculus

Alignment Length:	224	Identity:	57/224 - (25%)
Similarity:	92/224 - (41%)	Gaps:	48/224 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 DLWITKLLQVYDFDVEKCITRLWDNLAWRKSFGVYDITEANLNQEFLNDGSIYV---HNKDRDGK 105
            |..|.:.|:..||:::|....:..:|.|||...|..|.:.....:.|.|  .|.   |:.|:||:
Mouse   277 DEHILRFLRARDFNIDKAREIMCQSLTWRKQHQVDYILDTWTPPQVLLD--YYAGGWHHHDKDGR 339

  Fly   106 PLLILTI-----KKHSKSRNQEDLLR-ILVFWIERLQRDSNLDKI--------TIFMDMTGAGLS 156
            ||.:|.:     |...::..:|.||| :|....|.|:|.....|:        |..:|:.|..:.
Mouse   340 PLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMR 404

  Fly   157 NLDMGFIKS---IIGVFETKYPYVPNYILVHDLPFLLDAAFKLVKTFLPPEALKILKVTTKKDID 218
            :|....:|:   ||.|.|..||.....:|:...|.:....:.||..|:...       |.:|.:
Mouse   405 HLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDN-------TRRKFL- 461

  Fly   219 QYVDKDNCLKIWGGND--------DYVYK 239
                      |:.|||        ||:.|
Mouse   462 ----------IYAGNDYQGPGGLLDYIDK 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32407	NP_001261456.1	CRAL_TRIO	92..233	CDD:279044	38/160 (24%)
Sec14l1	NP_083053.2	Required for interaction and inhibitory function toward DDX58. /evidence=ECO:0000250\|UniProtKB:Q92503	1..510		57/224 (25%)
		PRELI	17..173	CDD:282550
		CRAL_TRIO_N	256..301	CDD:215024	6/23 (26%)
		CRAL_TRIO	326..490	CDD:279044	43/173 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820