DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32407 and SEC14L1

DIOPT Version :9

Sequence 1:	NP_001261456.1	Gene:	CG32407 / 38667	FlyBaseID:	FBgn0052407	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_001034662.3	Gene:	SEC14L1 / 6397	HGNCID:	10698	Length:	719	Species:	Homo sapiens

Alignment Length:	282	Identity:	68/282 - (24%)
Similarity:	112/282 - (39%)	Gaps:	70/282 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PSDQDP---TPE-------------QISQVKTSILQRLEKEPPAEPFHPNDLKRITDSDLWITKL 50
            ||..:|   ||:             .::.::.|.|.||.:.  .:..|...:.:    |..|.:.
Human   225 PSAPEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQW--LQETHKGKIPK----DEHILRF 283

  Fly    51 LQVYDFDVEKCITRLWDNLAWRKSFGVYDITEANLNQEFLNDGSIYV---HNKDRDGKPLLILTI 112
            |:..||:::|....:..:|.|||...|..|.|.....:.|.|  .|.   |:.|:||:||.:|.:
Human   284 LRARDFNIDKAREIMCQSLTWRKQHQVDYILETWTPPQVLQD--YYAGGWHHHDKDGRPLYVLRL 346

  Fly   113 -----KKHSKSRNQEDLLR-ILVFWIERLQRDSNLDKI--------TIFMDMTGAGLSNLDMGFI 163
                 |...::..:|.||| :|....|.|:|.....|:        |..:|:.|..:.:|....:
Human   347 GQMDTKGLVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGV 411

  Fly   164 KS---IIGVFETKYPYVPNYILVHDLPFLLDAAFKLVKTFLPPEALKILKVTTKKDIDQYVDKDN 225
            |:   ||.|.|..||.....:|:...|.:....:.||..|:...       |.:|.:
Human   412 KALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDN-------TRRKFL-------- 461

  Fly   226 CLKIWGGND--------DYVYK 239
               |:.|||        ||:.|
Human   462 ---IYAGNDYQGPGGLLDYIDK 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32407	NP_001261456.1	CRAL_TRIO	92..233	CDD:279044	38/160 (24%)
SEC14L1	NP_001034662.3	PRELI	17..173	CDD:368069
		CRAL_TRIO_N	256..301	CDD:215024	11/50 (22%)
		CRAL_TRIO	326..490	CDD:366224	43/173 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820