DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32407 and clvs2

DIOPT Version :9

Sequence 1:	NP_001261456.1	Gene:	CG32407 / 38667	FlyBaseID:	FBgn0052407	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_001020716.1	Gene:	clvs2 / 566769	ZFINID:	ZDB-GENE-041014-313	Length:	329	Species:	Danio rerio

Alignment Length:	244	Identity:	53/244 - (21%)
Similarity:	95/244 - (38%)	Gaps:	40/244 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TPEQISQVKTSILQRLEKEPPAEPFHPNDLKRITD-------------SDLWITKLLQVYDFDVE 59
            :||.:.:.|..:     ||.| :..| .|::.:.|             .|.:|.:.|:...|:..
Zfish     9 SPETLEKAKVEL-----KENP-DTLH-QDIQEVRDMIITRPDIGFLRTDDAFILRFLRARKFNHF 66

  Fly    60 KCITRLWDNLAWRKS----FGVYDITEANLNQEFLNDGSIYV-HNKDRDGKPLLILTIKKHSKSR 119
            :....|.....:|:.    |.....|:..:.|. |.||...| .|.||.|:.:|:|......:||
Zfish    67 EAFRLLAQYFEYRQQNLDMFKNLKATDPGIKQA-LKDGFPGVLSNLDRYGRKILVLFAANWDQSR 130

  Fly   120 -NQEDLLRILVFWIERLQRDSNLD-----KITIFMDMTGAGLSNLDMGFIKSIIGVFETKYPYVP 178
             ...|:||.::..:|.:..|..|.     .|..:.:.|....|.|....::..|...:..:|...
Zfish   131 YTFVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARF 195

  Fly   179 NYILVHDLPFLLDAAFKLVKTFLPPEALKILKVTTKKDIDQYVDKDNCL 227
            ..|...:.|:.:.|.:.:::.|        ||..|:|.|..:.:..|.|
Zfish   196 GGIHFVNQPWYIHALYTVIRPF--------LKDKTRKRIFMHGNNLNSL 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32407	NP_001261456.1	CRAL_TRIO	92..233	CDD:279044	34/143 (24%)
clvs2	NP_001020716.1	CRAL_TRIO_N	29..75	CDD:215024	7/45 (16%)
		SEC14	106..251	CDD:238099	32/139 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	293..329
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900