DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32407 and sec14l8

DIOPT Version :9

Sequence 1:	NP_001261456.1	Gene:	CG32407 / 38667	FlyBaseID:	FBgn0052407	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_001093463.1	Gene:	sec14l8 / 558964	ZFINID:	ZDB-GENE-060526-180	Length:	395	Species:	Danio rerio

Alignment Length:	247	Identity:	57/247 - (23%)
Similarity:	109/247 - (44%)	Gaps:	40/247 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 EQISQVKTSILQRLEKEPPAEPFHPNDLKRITDSDLWITKLLQVYDFDVEKCITRLWDNLAWRKS 74
            |.::|.:..:...|.:.|             :.||.::.:.|:..:|:::|....|..::.:||.
Zfish    14 EALAQFREKVQDVLPQCP-------------SQSDHFLLRWLRARNFNLQKSEAMLRKHIEFRKH 65

  Fly    75 FGVYDITE----ANLNQEFLNDGSIYVHNKDRDGKPLLI-----LTIKKHSKSRNQEDLLRILVF 130
            ..|..||.    ..:..::|:.|   :...||:|.|:..     |..|....|.:::||::..|.
Zfish    66 MKVDTITTEWQVPEVIDKYLSGG---MCGHDREGSPVWYDVIGPLDPKGLMHSASKQDLIKSKVR 127

  Fly   131 WIERLQRD---------SNLDKITIFMDMTGAGLSNLDMGFIKS---IIGVFETKYPYVPNYILV 183
            ..|.||:|         .|::.||:..|..|.|:.:|....|::   ::.:||..||.....:.|
Zfish   128 DCEILQKDCDRQSERLGRNIESITMVYDCEGLGMKHLYKPAIETYGEVLTMFEDNYPEGLKRLFV 192

  Fly   184 HDLPFLLDAAFKLVKTFLPPEALK---ILKVTTKKDIDQYVDKDNCLKIWGG 232
            ...|.|...|:.|||.||..:..:   :|....::.:.:|:|.:.....:||
Zfish   193 IKAPKLFPVAYNLVKHFLSEDTRRKVIVLGSNWQEVLQKYIDPEELPAYYGG 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32407	NP_001261456.1	CRAL_TRIO	92..233	CDD:279044	41/161 (25%)
sec14l8	NP_001093463.1	CRAL_TRIO_N	13..59	CDD:215024	10/57 (18%)
		SEC14	78..246	CDD:214706	42/170 (25%)
		GOLD_2	304..382	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820