DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32407 and Ttpa

DIOPT Version :9

Sequence 1:	NP_001261456.1	Gene:	CG32407 / 38667	FlyBaseID:	FBgn0052407	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_056582.1	Gene:	Ttpa / 50500	MGIID:	1354168	Length:	278	Species:	Mus musculus

Alignment Length:	177	Identity:	37/177 - (20%)
Similarity:	71/177 - (40%)	Gaps:	28/177 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 SDLWITKLLQVYDFDVEKCITRLWDNLAWR--KSFGVYDITEANLNQEFLNDGSI---------- 95
            :|.::.:.|:..|||::         ||||  |::..:......|:.: |...||
Mouse    48 TDAFLLRFLRARDFDLD---------LAWRLMKNYYKWRAECPELSAD-LRPRSILGLLKAGYHG 102

  Fly    96 YVHNKDRDGKPLLILTIKK-HSKSRNQEDLLRILVFWIERLQRDSNLDK--ITIFMDMTGAGLSN 157
            .:.::|..|..:||..|.. ..|.....|:.|:.:...|.:.::....:  :....|:.|..:|:
Mouse   103 VLRSRDSTGSRVLIYRIAYWDPKVFTAYDVFRVSLITSELIVQEVETQRNGVKAIFDLEGWQVSH 167

  Fly   158 ---LDMGFIKSIIGVFETKYPYVPNYILVHDLPFLLDAAFKLVKTFL 201
               :.....|.|..|....:|.....|.:.:.|.:..|.|.::|.||
Mouse   168 AFQITPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFL 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32407	NP_001261456.1	CRAL_TRIO	92..233	CDD:279044	25/126 (20%)
Ttpa	NP_056582.1	CRAL_TRIO_N	25..73	CDD:215024	10/33 (30%)
		CRAL_TRIO	99..248	CDD:279044	23/116 (20%)
		Phosphatidylinositol 3,4-bisphosphate binding. /evidence=ECO:0000269\|PubMed:23599266, ECO:0007744\|PDB:3W67	190..192		0/1 (0%)
		Phosphatidylinositol 4,5-bisphosphate binding. /evidence=ECO:0000269\|PubMed:23599266, ECO:0007744\|PDB:3W68	208..211		0/2 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900