DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32407 and hpo-28

DIOPT Version :9

Sequence 1:	NP_001261456.1	Gene:	CG32407 / 38667	FlyBaseID:	FBgn0052407	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_498232.3	Gene:	hpo-28 / 175798	WormBaseID:	WBGene00015148	Length:	567	Species:	Caenorhabditis elegans

Alignment Length:	246	Identity:	74/246 - (30%)
Similarity:	129/246 - (52%)	Gaps:	24/246 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DPTP-EQISQVKTSILQRLEKEPPAEPFH-PNDLKRITDSDLWITKLLQVYDFDVEKCITRLWDN 68
            |||. ..:.::::.|||    :|.....| .:|:.||...|.|:.:.|...::||:.....:.:.
Worm    20 DPTNLLAVHELRSRILQ----DPAISVKHLSDDVHRIRHEDWWLDRFLGSVNYDVDIAYAIMLEC 80

  Fly    69 LAWRKSFGVYDITEANLNQEFLNDGSIYVHNKDRDGKPLLILTIKKHSKSRNQED-LLRILVFWI 132
            |.||::|.|..|:..:| :..|::..:|:|.||...:.:|.:.:.|:   :|.:| ..::..|||
Worm    81 LKWRRNFEVDRISLLSL-KPLLDNQLMYLHGKDLQNRHMLWIMMNKY---KNGDDGFEKLFTFWI 141

  Fly   133 ERLQRD-SNLDKITIFMDMTGAGLSNLDMGFIKSIIGVFETKYPYVPN---YILVHDLPFLLDAA 193
            ||...: .....:|:|:||||.||.|:....:|.||  ..:|| |.||   .||:.:.|.:|:|:
Worm   142 ERHYMEYKGCQPLTVFIDMTGTGLKNMSFDAMKFII--HSSKY-YYPNSIESILIFENPAILNAS 203

  Fly   194 FKLVKTFLPPEALK----ILKVTTKKDIDQYVDKDNCLKIWGGNDDYVYKF 240
            :|::.::|...|..    :|...||..:..||.|.:.|:..||.|  .:||
Worm   204 WKVIGSWLESSAASQRHDLLTFVTKLSVTHYVPKSHLLEHQGGTD--TFKF 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32407	NP_001261456.1	CRAL_TRIO	92..233	CDD:279044	46/149 (31%)
hpo-28	NP_498232.3	SEC14	105..247	CDD:238099	46/147 (31%)
hpo-28	NP_498232.3	Motile_Sperm	<381..460	CDD:279029
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159698
Domainoid	1	1.000	79	1.000	Domainoid score	I5614
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D217631at33208
OrthoFinder	1	1.000	-	-		FOG0002427
OrthoInspector	1	1.000	-	-		otm14425
orthoMCL	1	0.900	-	-		OOG6_101230
Panther	1	1.100	-	-	O	PTHR46384
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.850