DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32407 and MOSPD2

DIOPT Version :9

Sequence 1:	NP_001261456.1	Gene:	CG32407 / 38667	FlyBaseID:	FBgn0052407	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_689794.1	Gene:	MOSPD2 / 158747	HGNCID:	28381	Length:	518	Species:	Homo sapiens

Alignment Length:	241	Identity:	73/241 - (30%)
Similarity:	135/241 - (56%)	Gaps:	12/241 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 EQISQVKTSIL----QRLEKE---PPAEPFHPNDLKRITDSDLWITKLLQVYDFDVEKCITRLWD 67
            |..:|.|..::    :|.|.|   ..::.:...|::|:...|.|:...|......|::.:..|.:
Human     3 ENHAQNKAKLISETRRRFEAEYVTDKSDKYDARDVERLQQDDNWVESYLSWRHNIVDETLKMLDE 67

  Fly    68 NLAWRKSFGVYDITEANLNQEFLNDGSIYVHNKDRDGKPLLILTIKKHSKSRNQEDLL---RILV 129
            :..|||...|.|:.|:::.:..|..|.||:|..|::|..|..:.:|.|.|  :|:.:|   :::.
Human    68 SFQWRKEISVNDLNESSIPRWLLEIGVIYLHGYDKEGNKLFWIRVKYHVK--DQKTILDKKKLIA 130

  Fly   130 FWIERLQRDSNLDKITIFMDMTGAGLSNLDMGFIKSIIGVFETKYPYVPNYILVHDLPFLLDAAF 194
            ||:||..:..|...:|:..|::..|::::||.|::.||..|:..||...:.|::.|:|:|::|||
Human   131 FWLERYAKRENGKPVTVMFDLSETGINSIDMDFVRFIINCFKVYYPKYLSKIVIFDMPWLMNAAF 195

  Fly   195 KLVKTFLPPEALKILKVTTKKDIDQYVDKDNCLKIWGGNDDYVYKF 240
            |:|||:|.|||:.:||.|:|.::..||..:......||.|.:.|.:
Human   196 KIVKTWLGPEAVSLLKFTSKNEVQDYVSVEYLPPHMGGTDPFKYSY 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32407	NP_001261456.1	CRAL_TRIO	92..233	CDD:279044	50/143 (35%)
MOSPD2	NP_689794.1	CRAL_TRIO	93..234	CDD:279044	50/142 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	252..308
		Motile_Sperm	327..431	CDD:279029
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147719
Domainoid	1	1.000	109	1.000	Domainoid score	I6349
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D217631at33208
OrthoFinder	1	1.000	-	-		FOG0002427
OrthoInspector	1	1.000	-	-		otm40598
orthoMCL	1	0.900	-	-		OOG6_101230
Panther	1	1.100	-	-	O	PTHR46384
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1928
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.840