DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32407 and AgaP_AGAP003734

DIOPT Version :9

Sequence 1:	NP_001261456.1	Gene:	CG32407 / 38667	FlyBaseID:	FBgn0052407	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	XP_310265.7	Gene:	AgaP_AGAP003734 / 1271467	VectorBaseID:	AGAP003734	Length:	296	Species:	Anopheles gambiae

Alignment Length:	251	Identity:	53/251 - (21%)
Similarity:	92/251 - (36%)	Gaps:	28/251 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PSDQDPTP-----EQISQVKTSILQRLEKEPPAEPFHPNDLKRITDSDLW----ITKLLQVYDFD 57
            |....|.|     |..:.|.| :.:.::::|....|..|.......:.||    ..|.||.|. .
Mosquito     7 PFKDSPEPLEVPKEHAANVDT-LYEWIKEQPRFPAFSKNHAHLFLHACLWNVDDAKKALQKYS-Q 69

  Fly    58 VEKCITRLWDNLAWRKSFGVYDITEANLNQEFLNDGSIYVHNKDRDGKPLLI--LTIKKHSKSRN 120
            :......::||         .||..|.:.........:.:.....:|..||.  |:....||...
Mosquito    70 IHANSPEIFDN---------RDIMGAGVQMTLNATHMVALPRTTPEGYRLLYYRLSDTDPSKMNF 125

  Fly   121 QEDLLRILVFWIERLQRDSNLDKITIFMDMTGAGLSNL---DMGFIKSIIGVFETKYPY-VPNYI 181
            .|.:....:|...::..|..::...:..||.|..|.:|   ....::..:...:..:|. :....
Mosquito   126 TEAVKSFCMFNDAQISVDGIMEGYIVIFDMKGVRLGHLARVQFSPLRVFMSYIQDAHPVRLKKIY 190

  Fly   182 LVHDLPFLLDAAFKLVKTFLPPEALKILKVTTKKDIDQYVDKDNCLKIWGGNDDYV 237
            :||...| ::....|||..:..|.|.:|:.||... ::.|..|...|.:||..|.|
Mosquito   191 IVHTASF-INQVMALVKPLIKSELLGLLQFTTAGP-EEIVGVDYLPKDFGGPFDEV 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32407	NP_001261456.1	CRAL_TRIO	92..233	CDD:279044	30/146 (21%)
AgaP_AGAP003734	XP_310265.7	CRAL_TRIO_N	25..67	CDD:215024	10/42 (24%)
AgaP_AGAP003734	XP_310265.7	SEC14	96..239	CDD:238099	29/144 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900