DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10483 and VTC3

DIOPT Version :9

Sequence 1:	NP_648000.1	Gene:	CG10483 / 38666	FlyBaseID:	FBgn0035649	Length:	671	Species:	Drosophila melanogaster
Sequence 2:	NP_015306.1	Gene:	VTC3 / 856088	SGDID:	S000005940	Length:	835	Species:	Saccharomyces cerevisiae

Alignment Length:	168	Identity:	49/168 - (29%)
Similarity:	68/168 - (40%)	Gaps:	42/168 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFAEHLTAHITPEWRKQYINYEEMKAMLYAAIEQSPSAELVEREMVTRYFAKFDEEFFHYCDKE 65
            |.|...|...:.|.|:..||:||.:|.:|..::...      .|..|..:..:.:.:|....|||
Yeast     1 MLFGIKLANDVYPPWKDSYIDYERLKKLLKESVIHD------GRSSVDSWSERNESDFVEALDKE 59

  Fly    66 LAKINTFYSEKMAEATRKYGSLRSELTEALEMGHPKKLPAWKRRTPLGKKNVPARKIQDLKLAFS 130
            |.|:.||...|.....||...| .|.|::                        |.|||.:.   |
Yeast    60 LEKVYTFQISKYNAVLRKLDDL-EENTKS------------------------AEKIQKIN---S 96

  Fly   131 EFYLGLI--------LLQNYQNLNFTGFRKILKKHDKL 160
            |.:...:        .|.|:..||||||.||:||||||
Yeast    97 EQFKNTLEECLDEAQRLDNFDRLNFTGFIKIVKKHDKL 134

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10483	NP_648000.1	SPX_XPR1_like	2..159	CDD:269898	45/164 (27%)
		SPX	3..162	CDD:281146	48/166 (29%)
		EXS	260..600	CDD:281164
VTC3	NP_015306.1	COG5036	1..561	CDD:227369	49/168 (29%)
VTC3	NP_015306.1	VTC1	673..803	CDD:227589
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343540
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.569298	Normalized mean entropy	S1995
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.790