DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10483 and VTC2

DIOPT Version :9

Sequence 1:	NP_648000.1	Gene:	CG10483 / 38666	FlyBaseID:	FBgn0035649	Length:	671	Species:	Drosophila melanogaster
Sequence 2:	NP_116651.1	Gene:	VTC2 / 850544	SGDID:	S000001890	Length:	828	Species:	Saccharomyces cerevisiae

Alignment Length:	164	Identity:	49/164 - (29%)
Similarity:	72/164 - (43%)	Gaps:	33/164 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFAEHLTAHITPEWRKQYINYEEMKAMLYAAIEQSPSAELVEREMVTRYFAKFDEEFFHYCDKE 65
            |.|...|...:.|.|:..|||||.:|..|     :..|.:....:...|:....:.:|....|||
Yeast     1 MLFGVKLANEVYPPWKGSYINYEGLKKFL-----KEDSVKDGSNDKKARWDDSDESKFVEELDKE 60

  Fly    66 LAKINTFYSEKMAEATRKYGSLRSELTEALEMGHPKKLPAWKRRTPLGKKNVPA----RKIQDLK 126
            |.|:..|       ..:||.:|...|:      |.:|    :..|....|.:.|    |.:::|.
Yeast    61 LEKVYGF-------QLKKYNNLMERLS------HLEK----QTDTEAAIKALDADAFQRVLEELL 108

  Fly   127 LAFSEFYLGLILLQNYQNLNFTGFRKILKKHDKL 160
            ...:|       |.|::.||||||.||:||||||
Yeast   109 SESTE-------LDNFKRLNFTGFAKIVKKHDKL 135

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10483	NP_648000.1	SPX_XPR1_like	2..159	CDD:269898	45/160 (28%)
		SPX	3..162	CDD:281146	48/162 (30%)
		EXS	260..600	CDD:281164
VTC2	NP_116651.1	COG5036	1..555	CDD:227369	49/164 (30%)
VTC2	NP_116651.1	VTC1	662..791	CDD:227589
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343544
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.569298	Normalized mean entropy	S1995
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.790