DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10483 and AT1G35350

DIOPT Version :9

Sequence 1:	NP_648000.1	Gene:	CG10483 / 38666	FlyBaseID:	FBgn0035649	Length:	671	Species:	Drosophila melanogaster
Sequence 2:	NP_174768.2	Gene:	AT1G35350 / 840424	AraportID:	AT1G35350	Length:	751	Species:	Arabidopsis thaliana

Alignment Length:	767	Identity:	194/767 - (25%)
Similarity:	320/767 - (41%)	Gaps:	185/767 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFAEHLTAHITPEWRKQYINYEEMKAML---YAAIEQSPSAELVEREM------------VTRY 50
            |||.:...|.:.|||::.|::|..:|.:|   ..:.::|.|..:::|::            .:|.
plant     1 MKFGKEYVAQMIPEWQQAYMDYTCLKTILREIKTSQKRSESQGVLKRKLSGRRNFSGLTKRYSRT 65

  Fly    51 FAKFDEE-----------------------------------FFHYCDKELAKINTFYSEKMAEA 80
            |:..|.|                                   ||...|.|..|:|.||...:.|.
plant    66 FSSRDLENHDIMVHATTGDDGFEKYETTILKVSEVGRESELVFFKTLDLEFDKVNRFYRSNVEEL 130

  Fly    81 TRKYGSLRSEL--------------------------------------TEALEMG--------- 98
            .::...|..::                                      |.|.|||
plant   131 VKEAVVLNRQMDALIAYRIKLDQPSTSWSCSETVSVDINALDSKEQKGKTLAEEMGIKVEENVSN 195

  Fly    99 --------HPKKLPAWKR-------RTPLG-----------------KKNVPARKIQD-LKLAFS 130
                    .|:.|....|       ..||.                 |:|:  :||:: ||..|.
plant   196 GGDSTKETAPEALSVLDRIRLNKNQENPLSTIRNVLKLSNKEDIKFTKENL--KKIEERLKNVFI 258

  Fly   131 EFYLGLILLQNYQNLNFTGFRKILKKHDKLLSVDYGARWRTDHVEAAHFYTNKDIDRLIQETEQA 195
            |||..|..|:||..||.....||:||:|| :::...|:...:.|:.::..::.:|::|:...|..
plant   259 EFYRKLRHLKNYSFLNTLAISKIMKKYDK-IALRNAAKLYMEMVDKSYLTSSDEINKLMLRVESI 322

  Fly   196 VTQDIEGGDRQRAMKRLRVPPLGEQQSPWTTFKVGLFSGAFVVLFITVVIAAMFYGFGEN--WRA 258
            ..:...|.:|.:.|..||  |...::....||..|.|.|..|    ::|||...:....|  ...
plant   323 FVEHFAGSNRSKGMNLLR--PKVTKEKHRITFSTGFFVGCTV----SLVIALGLFIHARNIMGAV 381

  Fly   259 GMRMFRAPFLIIECLF--------LWGVNVYGWRSSGVNHVLIFELDPRNHLSEQNIMEVASVFG 315
            |.:::......:..||        ::..|:|.|:...||:..||.......|...:::.::...|
plant   382 GHKLYMETMFPLYSLFAFVVLHMIMYASNIYFWKRYRVNYPFIFGFKEGTELGYGHVLLLSFGLG 446

  Fly   316 VIWACCVL--SYIFCDPLGIPQY-----AAPLCLYTLMAAFLLNPTKTFHHEARFWAIRILIRVI 373
            .:..|.||  ..:..|| ....|     ..||.:..|:.|..:.|...|:..:||:.:.:|.|.|
plant   447 TLALCAVLVNMDMEMDP-NTNDYKTITELVPLFVVALVIAISVCPFNIFYRSSRFFFLMVLFRCI 510

  Fly   374 MAPFCFVNFADFWLADQLNSMVPAFLDIPFLICFFGRSPTWHKAGKAASHC--VEYVSLLHPIVA 436
            .||...||..||:|||||.|.|.|...:.|.||::|    |....:..|.|  .:..|..:.|||
plant   511 AAPLYKVNLPDFFLADQLTSQVQALRSLEFYICYYG----WGDFKQRQSTCKSSDVYSTFYFIVA 571

  Fly   437 IMPAYFRFAQCIRRY---RDTKESFPHLVNAAKYATSFFVVIFAHKYHTTTDTYPLSKENPW-FY 497
            ::|.:.||.||:||.   :|..:.|    ||.||..:...|..       ...:.:::.|.| ..
plant   572 VIPYWSRFLQCVRRLIEEKDVSQGF----NALKYLLTIVAVCL-------RTAFSINRGNDWKIA 625

  Fly   498 CWITAAIFSSCYAYTWDIKMDWGLF--DSKAGDNRFLREEIVYSSTWFYYFGIIEDLILRFSWTL 560
            .|:.:.: ::.|...|||..||||.  .||:    :|||:::......||..::.:::||.:|..
plant   626 AWVFSGL-ATFYGTYWDIVYDWGLLHRPSKS----WLREKLLVPHKSVYYVAMVVNVVLRLAWLQ 685

  Fly   561 SMSLIEAGYIEGDVMMTILSPLEVFRRFIWNYFRLENEHLNNVGKFRAVRDI 612
            ::......::..:.|:.:::.||:.||.|||:||||||||||||||||.:.:
plant   686 TVLDFNISFLHRETMVALIAILEIIRRGIWNFFRLENEHLNNVGKFRAFKSV 737

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10483	NP_648000.1	SPX_XPR1_like	2..159	CDD:269898	57/286 (20%)
		SPX	3..162	CDD:281146	58/288 (20%)
		EXS	260..600	CDD:281164	102/362 (28%)
AT1G35350	NP_174768.2	SPX_PHO1_like	2..295	CDD:269897	59/295 (20%)
		SPX	3..300	CDD:281146	59/299 (20%)
		EXS	391..725	CDD:281164	102/354 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	1	0.900	-	-		OOG6_100965
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.840