DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10483 and AT1G26730

DIOPT Version :9

Sequence 1:	NP_648000.1	Gene:	CG10483 / 38666	FlyBaseID:	FBgn0035649	Length:	671	Species:	Drosophila melanogaster
Sequence 2:	NP_173995.1	Gene:	AT1G26730 / 839214	AraportID:	AT1G26730	Length:	750	Species:	Arabidopsis thaliana

Alignment Length:	770	Identity:	193/770 - (25%)
Similarity:	324/770 - (42%)	Gaps:	173/770 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFAEHLTAHITPEWRKQYINYEEMKAML---YAAIEQSPSAELVERE---------MVTRY--- 50
            |||.:.....:.|||::.|::|..:|::|   ..:.::|....:::|:         :..||
plant     1 MKFGKDFVRQMIPEWQQAYMDYAGLKSILQEIQTSRKRSERPGILKRKLSGSRNFSGLTKRYSRT 65

  Fly    51 ---------------------FAKFDE--------------EFFHYCDKELAKINTFYSEKMAEA 80
                                 |.:::.              .||...|.|..|:|.||..|:.|.
plant    66 ASTREPEIQDILVHATTGDDGFERYETTILEVAEAGRESELAFFKTLDLEFDKVNHFYRSKVEEM 130

  Fly    81 TRKYGSLRSEL-------------------------------------TEALEMG---------- 98
            .::...|..::                                     |.|.|||
plant   131 VKEAVVLNKQMDALIAFRIKVERPSSSWSCSETVSVDMNALDSNDQRNTLAEEMGIRVEGNGSNG 195

  Fly    99 -------HPKKLPAWKR-------RTPLGK-KNV--------------PARKIQD-LKLAFSEFY 133
                   .|:.|...:|       .|||.. |||              ..:||:: ||..|.|||
plant   196 GDSTKESVPQVLSVLERIRLNKTQETPLSTIKNVLKLSNQEELKFTRENLKKIEERLKNVFIEFY 260

  Fly   134 LGLILLQNYQNLNFTGFRKILKKHDKLLSVDYGARWRTDHVEAAHFYTNKDIDRLIQETEQAVTQ 198
            ..|..|:||..||.....||:||:||:.|.. .|:...:.|:.::..::.:|::|:...|....:
plant   261 RKLRHLKNYSFLNTLAISKIMKKYDKIASRS-AAKPYMEMVDKSYLTSSDEINKLMLRVESTFVE 324

  Fly   199 DIEGGDRQRAMKRLRVPPLGEQQSPWTTFKVGLFSGAFVVLFITVVIAAMFYGFGEN--WRAGMR 261
            ...|.:|.:.|..||  |..:::....||..|.|.|..|    ::|:|.:.:....|  ...|.:
plant   325 HFAGLNRSKGMNLLR--PKVKKEKHRITFSTGFFVGCTV----SLVVALVMFIHARNIMGAVGHK 383

  Fly   262 MFRAPFLIIECLF--------LWGVNVYGWRSSGVNHVLIFELDPRNHLSEQNIMEVASVFGVIW 318
            ::......:..||        ::..|:|.|:...||:..||.......|..::::.::...|.:.
plant   384 VYMETMFPLYSLFAFVVLHMIMYASNIYFWKRYRVNYPFIFGFKEGTELGYRHVLLLSFGLGTLA 448

  Fly   319 ACCVLSYI--FCDPLGIPQYAA-----PLCLYTLMAAFLLNPTKTFHHEARFWAIRILIRVIMAP 376
            .|.||..:  ..|| ....|..     |:.:..|:.|.|..|...|:..:|.:.:.::.|.|.||
plant   449 LCAVLINLDMEMDP-NTNDYKTMTELLPMFILALVVAILFCPFNIFYRSSRVFFLMVVFRCIAAP 512

  Fly   377 FCFVNFADFWLADQLNSMVPAFLDIPFLICFFGRSPTWHKAGKAASHCVEYVSLLHPIVAIMPAY 441
            ...||..||:|||||.|.|.|...:.|.||::|.....|:.....|.  :..|..:.|||::|.:
plant   513 LYKVNLPDFFLADQLTSQVQALRSLEFYICYYGWGDFKHRQNTCRSS--DVYSTFYFIVAVIPYW 575

  Fly   442 FRFAQCIRRY---RDTKESFPHLVNAAKYATSFFVVIFAHKYHTTTDTYPLSKENPW-FYCWITA 502
            .||.||:||.   .|:.:.:    ||.||..:...|..       ...|..::.|.| ...|:.:
plant   576 SRFLQCVRRLIEENDSSQGY----NALKYLLTVVAVCL-------RTAYSFNRGNIWKISAWVFS 629

  Fly   503 AIFSSCYAYTWDIKMDWGLFDSKAGDNRFLREEIVYSSTWFYYFGIIEDLILRFSWTLSMSLIEA 567
            |: ::.|...|||..||||....:  ...|||:::......||..|:.:::||.:|..::.....
plant   630 AL-ATFYGTYWDIVFDWGLLHRPS--KHLLREKLLVPHKAVYYVAIVLNIVLRMAWLQTVLDFNL 691

  Fly   568 GYIEGDVMMTILSPLEVFRRFIWNYFRLENEHLNNVGKFRAVRDISVAPMDCSDQ 622
            .::..:.|:.:|:.||:.||.|||:||||||||||||||||.:.:.: |.:.:::
plant   692 SFLHRETMIALLAALEIIRRGIWNFFRLENEHLNNVGKFRAFKSVPL-PFNYNEE 745

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10483	NP_648000.1	SPX_XPR1_like	2..159	CDD:269898	57/283 (20%)
		SPX	3..162	CDD:281146	58/285 (20%)
		EXS	260..600	CDD:281164	100/358 (28%)
AT1G26730	NP_173995.1	SPX_PHO1_like	2..294	CDD:269897	60/292 (21%)
		SPX	3..299	CDD:281146	60/296 (20%)
		SPX	<212..286	CDD:271919	25/73 (34%)
		EXS	390..724	CDD:281164	100/350 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	1	0.900	-	-		OOG6_100965
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840