DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10483 and AT1G14040

DIOPT Version :9

Sequence 1:	NP_648000.1	Gene:	CG10483 / 38666	FlyBaseID:	FBgn0035649	Length:	671	Species:	Drosophila melanogaster
Sequence 2:	NP_172857.2	Gene:	AT1G14040 / 837965	AraportID:	AT1G14040	Length:	813	Species:	Arabidopsis thaliana

Alignment Length:	838	Identity:	194/838 - (23%)
Similarity:	312/838 - (37%)	Gaps:	265/838 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFAEHLTAHITPEWRKQYINYEEMKAM-------------------------------LYAAI- 33
            |||.:..::.:.|||::.|::|:.:|.:                               ||.|.
plant     1 MKFGKEFSSQMVPEWQQAYMDYDFLKTLLKEIITFKRRTNNAPSHGGAKTGGGLNRKLTLYRAFS 65

  Fly    34 --------EQSPSAELVERE---------------------------MVTRYFAKFDEEFFHYCD 63
                    ::|.|:..||..                           |......:::..||...|
plant    66 GLVSTPRHKRSNSSHDVEEGVQLTGSMRSGPILVNTTASHGYETTFLMAAEEGGEYELVFFRRLD 130

  Fly    64 KELAKINTFYSEKMAEATRKYGSLRSELTEALEMGHPKKLP---AWKRR---------------- 109
            .|..|::.||.:|:.|..::...|..::...:......:.|   .|:.|
plant   131 DEFNKVDKFYRKKVEEVLKEAAMLNKQMDALIAFRVKVENPDGWRWEERTVEMTRLASDIATSAA 195

  Fly   110 -----TPLGKKNVPAR------------------------------------------------- 120
                 ||.|.|::..|
plant   196 ALSASTPAGAKSMKVRSQEHMEAIQEGGSSRAGLMEDDEEDEDEQNETSVVSTGAIDNETTTSRM 260

  Fly   121 -----------------------------------------------KIQD-LKLAFSEFYLGLI 137
                                                           |::: ||.||.|||..|.
plant   261 RGARPSPIDVLGRVKINNTKETPRSTIKGVLKVSKQTDLKFSRENLMKVEESLKRAFIEFYQKLR 325

  Fly   138 LLQNYQNLNFTGFRKILKKHDKLLSVDYGARWRTDHVEAAHFYTNKDIDRLIQETEQAVTQDIEG 202
            ||::|..||...|.|||||:||:.|.| ..:.....|::::..::.::.||::..|....:....
plant   326 LLKSYSFLNVLAFSKILKKYDKITSRD-ATKPYMKVVDSSYLGSSDEVMRLMERVEATFIKHFAN 389

  Fly   203 GDRQRAMKRLRVPPLGEQQSPWTTFKVGLFSGAFVVLFITVV-----------------IAAMF- 249
            .:|.:||..||  |..:::....||..|..:|....|.:.:|                 :..||
plant   390 ANRAKAMNILR--PKAKRERHRITFSTGFSAGCVFSLIVALVAIIRTRNLLEMEGQKEYMNTMFP 452

  Fly   250 ----YGFGENWRAGMRMFRAPFLIIECLFLWGVNVYGWRSSGVNHVLIFELDPRNHLSEQNIMEV 310
                :||                |:..:.::..|:|.||...||:..||.......|..:.::.|
plant   453 LYSLFGF----------------IVLHIIVYAANIYYWRRYRVNYSFIFGFKQGTELGYRQVLLV 501

  Fly   311 ASVFGVIWACCVLSYIFCDPLGIPQYAA--------PLCLYTLMAAFLLNPTKTFHHEARFWAIR 367
            ....||:...|||:.:  |....|:..|        ||.|...|...|:.|...|:..:||:.:.
plant   502 GFSIGVLALLCVLANL--DMEADPKTKAYQARTEILPLILLAAMFIVLVLPFNYFYRSSRFFFLT 564

  Fly   368 ILIRVIMAPFCFVNFADFWLADQLNSMVPAFLDIPFLICFFGRSPTWHKAGKAASHCVE---YVS 429
            .|...:.||...|...||:|.|||.|.|.|...|.|.||::|    |.......|.|.|   |.:
plant   565 CLFHCLAAPLYKVTLPDFFLGDQLTSQVQAIRSIEFYICYYG----WGDFRHRKSTCKESDVYNT 625

  Fly   430 LLHPIVAIMPAYFRFAQCIRRYRDTKESFPHL-VNAAKYATSFFVVIFAHKYHTTTDTYPLSKEN 493
            ... |||::|...|..||:||..:.|.  |.. .|..||    |:.|.|....|   .|.:.|..
plant   626 FFF-IVAVIPYVSRLLQCLRRLFEEKN--PEQGYNGLKY----FLTIVAVCLRT---AYSIQKGQ 680

  Fly   494 PWFYCW-ITAAIFS---SCYAYTWDIKMDWGLFDSKAGDNRFLREEIVYSSTWFYYFGIIEDLIL 554
               ..| :.||:||   :.:...||...||||. ::...||:||::::......|:..::.:::|
plant   681 ---VAWRVLAAVFSFIAAIFCTYWDFVHDWGLL-NRTSKNRWLRDKLLVPQKKVYFIAMVLNVLL 741

  Fly   555 RFSWTLSMSLIEAGYIEGDVMMTILSPLEVFRRFIWNYFRLENEHLNNVGKFRAVRDI 612
            ||:|..::......::....|:.|::.||:.||.|||:|||||||||||||:||.:.:
plant   742 RFAWIQTVLDFNFSFMHRQTMVAIVASLEIIRRGIWNFFRLENEHLNNVGKYRAFKSV 799

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10483	NP_648000.1	SPX_XPR1_like	2..159	CDD:269898	54/344 (16%)
		SPX	3..162	CDD:281146	55/346 (16%)
		EXS	260..600	CDD:281164	106/355 (30%)
AT1G14040	NP_172857.2	SPX_PHO1_like	2..355	CDD:269897	58/353 (16%)
		SPX	3..360	CDD:281146	57/357 (16%)
		SPX	<284..347	CDD:271919	20/62 (32%)
		EXS	451..787	CDD:281164	109/371 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	1	0.900	-	-		OOG6_100965
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840