DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10486 and HXT5

DIOPT Version :9

Sequence 1:	NP_647998.2	Gene:	CG10486 / 38664	FlyBaseID:	FBgn0035647	Length:	706	Species:	Drosophila melanogaster
Sequence 2:	NP_011964.1	Gene:	HXT5 / 856496	SGDID:	S000001138	Length:	592	Species:	Saccharomyces cerevisiae

Alignment Length:	474	Identity:	98/474 - (20%)
Similarity:	169/474 - (35%)	Gaps:	119/474 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   237 IFFLGSILGGLAYGHFADHCGRVAALVSSCFLALVGSLATSMSTD-FFTFAISRFLVGASYDTCF 300
            ||.:|..:||:......|..||...|::...:..:|.:....|.| ::.:.|.|.:.|.......
Yeast   142 IFNIGCAIGGIVLSKLGDMYGRKIGLMTVVVIYSIGIIIQIASIDKWYQYFIGRIISGLGVGGIT 206

  Fly   301 TMVYILVLEYVGPKY--RTLVANLSLALFYSPF----TMVMPWIALSAGNWRRFSSFTSLPI--- 356
            .:..:|:.| |.||.  .|||:...|.:.:..|    |........::..||       :|:
Yeast   207 VLAPMLISE-VSPKQLRGTLVSCYQLMITFGIFLGYCTNFGTKNYSNSVQWR-------VPLGLC 263

  Fly   357 ----VLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKKQVSKEILDL-FEASCTQFYKEE 416
                :..:.....:|||.|:||.||:|::|   .:::...||......::.| .|...:....|.
Yeast   264 FAWSIFMIVGMTFVPESPRYLVEVGKIEEA---KRSLARANKTTEDSPLVTLEMENYQSSIEAER 325

  Fly   417 LDGRDFTVLSIFKRKRMARYMILMILIWMSISLVYDGHVRAASVLDSENIFLFF--TIACATELP 479
            |.|.......:..:.:|.|..::.::|            ::...|..:|.|.::  ||..|..|.
Yeast   326 LAGSASWGELVTGKPQMFRRTLMGMMI------------QSLQQLTGDNYFFYYGTTIFQAVGLE 378

  Fly   480 GNI--LVIL-------------TLDRAGRR----W-------CSFFYTSLSGVFSLLGASFQNRA 518
            .:.  .::|             |:||.|||    |       |...|.|: ||..|    :.|..
Yeast   379 DSFETAIVLGVVNFVSTFFSLYTVDRFGRRNCLLWGCVGMICCYVVYASV-GVTRL----WPNGQ 438

  Fly   519 NMRMSALAGR------FFSNICYNIGLQWA-------AEILPTVVRAQGVAFIHT----MGFVAM 566
            :...|..||.      .|...|:  ...||       :|..|..||.:.::....    .||:..
Yeast   439 DQPSSKGAGNCMIVFACFYIFCF--ATTWAPVAYVLISESYPLRVRGKAMSIASACNWIWGFLIS 501

  Fly   567 LMSPPVVYLSKKSLSSTLIVLGALGIFGGLLAL------------FLPETLNHELPETLSDGAQF 619
            ..:|              .:..|:..:.|.:.:            |:|||....|.|.   ...:
Yeast   502 FFTP--------------FITSAINFYYGYVFMGCMVFAYFYVFFFVPETKGLTLEEV---NEMY 549

  Fly   620 GKNQRIWHMPCCGPGSRKS 638
            .:|...|......|.||::
Yeast   550 EENVLPWKSTKWIPPSRRT 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	92/446 (21%)
CG10486	NP_647998.2	MFS	231..602	CDD:119392	88/436 (20%)
HXT5	NP_011964.1	Sugar_tr	89..549	CDD:395036	93/453 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000