Protein Alignment CG10486 and TPO1

DIOPT Version :10

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_013072.1
• Gene: TPO1 / 850631
• SGDID: S000003951
• Length: 586
• Species: Saccharomyces cerevisiae
• Alignment Length: 419
• Identity: 80/419 - (19%)
• Similarity: 134/419 - (31%)
• Gaps: 104/419 - (24%)

  Fly   237 IFFLGSILGGLAYGHFADHCGRVAALVSSCFLALVGSLATSMSTDFFTFAISRFLVGASYDTCFT 301
            :|.||.....:.|...::..||...||.|.|...:...|.:.:.:..|..|.||..|........
Yeast   190 LFVLGFAASPVIYAPLSELYGRKGVLVLSAFGFALFQFAVATAENLQTIFICRFFGGFIGAAPMA 254

  Fly   302 MVYILVLEYVGPKYR-TLVANLSLALFYSP-FTMVMPWIALSAGNWR------------------ 346
            :|.....:......| ..:|..||.:|..| .:.||.........||
Yeast   255 VVPAAFADMFDTNVRGKAIALFSLGVFVGPILSPVMGSYIAQRTTWRWLEYVVGCFASAVFVAIV 319

  Fly   347 RFSSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKKQVSKEILDLFEASCTQ 411
            .|...|..|.:|...:..:..:|..|.:.....|..|.| |::::   |.|::.|:.||......
Yeast   320 LFFEETHHPTILVNKAKQMRKQSNNWGIHAAHEDVELSI-KDIVQ---KTVTRPIIMLFVEPLLL 380

  Fly   412 F---YKEELDGRDFTVLSIFKRKRMARY-----------------MILMILIWMSISLVYDGHVR 456
            |   |...:.|..:.:|..:....:..|                 |:....||. :...|....|
Yeast   381 FVTIYNSFVYGILYLLLEAYPLVFVEGYGFTENGELPYIALIIGMMVCAAFIWY-MDNDYLKRCR 444

  Fly   457 AASVLDSENIFLFFTIACATELPGNILVILTLDRAGRRWCSFFYTSLSGVFSLLGASF------- 514
            |...|..| ..|:..:...|..|..||...        |..::...:..:...:|.:|
Yeast   445 AKGKLVPE-ARLYAMVIAGTVFPIGILWFC--------WTGYYPHKIHWMVPTVGGAFIGFGLMG 500

  Fly   515 ----------QNRANMRMSALAGRFFS----NICY---------NIGLQWAAEILPTVVRAQGVA 556
                      ::...:..||:|...|.    ..|:         .:|:.||..:|       |:
Yeast   501 IFLPCLNYIIESYLLLAASAVAANTFMRSAFGACFPLFAGYMFRGMGIGWAGLLL-------GL- 557

  Fly   557 FIHTMGFVAMLMSPPVVYLS------KKS 579
                  |.|.::..|:::|.      |||
Yeast   558 ------FAAAMIPVPLLFLKYGESIRKKS 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	80/419 (19%)
TPO1	NP_013072.1	MFS_Tpo1_MDR_like	156..577	CDD:340881	77/414 (19%)