DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10486 and OCT4

DIOPT Version :9

Sequence 1:	NP_647998.2	Gene:	CG10486 / 38664	FlyBaseID:	FBgn0035647	Length:	706	Species:	Drosophila melanogaster
Sequence 2:	NP_188702.2	Gene:	OCT4 / 821613	AraportID:	AT3G20660	Length:	526	Species:	Arabidopsis thaliana

Alignment Length:	560	Identity:	140/560 - (25%)
Similarity:	246/560 - (43%)	Gaps:	91/560 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 RRSWETDDYIDFDDLLP-MIGQFGRFQIRLFLFMIPFCFITAFVYLGQIFMCLTPPKYYCYVPEL 148
            ::..|.::.:..|::|. ..|:|||:|::.|:.......:.||..:..|| ....|::.|.
plant    23 KKEAEGEERLCIDEMLQRYCGEFGRWQLKHFVLTCIAWALEAFHTMVMIF-ADQEPEWRCV---- 82

  Fly   149 LHTPVELRKELSIPKEKDGSYSRCRMYNTNYTKIHFAENPSAYINTSLPTIPCKKGYVFEQEGRA 213
                                .|.||:.:.|...     :||::..|:      .||
plant    83 --------------------GSDCRVGSLNCEL-----DPSSWEWTA------GKG--------- 107

  Fly   214 FESATMEFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFAD-HCGRVAALVSSCFLALVGSLATS 277
             .|...|:|.:|.|.......|.:||.|.::|...:||.:| ..||..:|...|.:..:..:||:
plant   108 -SSTVSEWGLICGDKYKVGLVQALFFAGCMIGAGVFGHLSDSKLGRKGSLTVVCIINAIFGIATA 171

  Fly   278 MSTDFFTFAISRFLVGASYDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFTMVMPWIALSA 342
            .|.:::|:.:.|||.|.|........::|..|.:||..|. ||.:|...|:|....|:..||...
plant   172 FSPNYWTYVVLRFLTGFSTGGVGLTAFVLATEPIGPSKRG-VAGMSTFYFFSAGIAVLSGIAYVF 235

  Fly   343 GNWRRFSSFTSLPIVLAMFSFCLLP---ESARWLVSVGEIDKALEILKNVIEVNKKQVSKEILDL 404
            .:||.....:|||.:|  |...::|   ||.||.:..|::|:|::::.::.:.|.:.:
plant   236 RSWRELFIVSSLPSLL--FLLIVIPFISESPRWYLVRGKVDEAMKLMHSIAKTNGRHI------- 291

  Fly   405 FEASCTQFYKEELDGRD------------FTVLSIFKRKRMARYMILMILIWMSISLVYDGHVRA 457
             .|..|....::::..:            ..:||...|.|    :::.:.|..::|:||.|....
plant   292 -PAGVTLALDDDVENNNGERNTAVEGSLKDVILSPLMRMR----LVISVAISFTVSIVYYGLSLN 351

  Fly   458 ASVLDSENIFLFFTIACATELPGNILVILTLDRAGRRWCSFFYTSLSGVFSLLGASFQNRA---N 519
            ...|.: |::|...:...:|:|...:..:.||:.||:..|......|.||.|:|.|.....   :
plant   352 VGNLKT-NLYLNVFVNAVSEMPAFAITAVLLDKYGRKPLSIGTQWFSCVFCLVGFSVWGAGPWKS 415

  Fly   520 MRM-SALAGRFFSNICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVVYLSKKSLSST 583
            :|| |.:.|.|.....||:...:.||:.|||||...:........:..:::|.||.|.::   ..
plant   416 VRMVSGVLGIFGMAGTYNLLFIYIAELFPTVVRNAALGCATQAAQMGAILAPFVVVLGEE---LP 477

  Fly   584 LIVLGALGIFGGLLALFLPETLNHELPETLSDGAQFGKNQ 623
            ..|....|:.||.||.:||||||..|.:|:     ||.::
plant   478 FGVFAVCGLVGGGLAFYLPETLNKPLYDTM-----FGMHE 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	134/527 (25%)
CG10486	NP_647998.2	MFS	231..602	CDD:119392	101/390 (26%)
OCT4	NP_188702.2	MFS_OCT_plant	90..496	CDD:340936	112/445 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010