Protein Alignment CG10486 and slc22a21

DIOPT Version :10

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_001295487.1
• Gene: slc22a21 / 799908
• ZFINID: ZDB-GENE-091118-62
• Length: 546
• Species: Danio rerio
• Alignment Length: 564
• Identity: 143/564 - (25%)
• Similarity: 259/564 - (45%)
• Gaps: 50/564 - (8%)

  Fly    95 DFDDLLPMIGQFGRFQIRLF----LFMIPFCFI-TAFVYLGQIFMCLTPPKYYCYVPELLHTPVE 154
            |:::....:|.:|.||..:|    |.:||..|. .:.|:||.      .|.::|.:||.|:....
Zfish     5 DYEEQTAFLGAWGPFQKTVFSLLCLSIIPNGFTGLSIVFLGD------TPAHHCRIPETLNLTAG 63

  Fly   155 LRKELSIPKEK---DGSYSRCRMYNTNYTKIHFAEN---PSAYINTS-LPTIPCKKGYVFEQEGR 212
            .| ..|:|:.:   |...|||.....:..| ::::.   |...:|.| :|...|..|:::::|
Zfish    64 WR-NASVPRPQPHGDPRASRCYRLRLDLVK-NYSDGGLLPGLDVNVSEIPREECADGWIYDKE-- 124

  Fly   213 AFESATMEFGW--LCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFLALVGSLA 275
             ..|:|:...|  :|.||..:.....|||.|.:.|.:..|..:|..||...|..:..:..:.::.
Zfish   125 -IYSSTIVSEWDLVCSDDWKSPLTSSIFFCGVLTGSVISGPVSDRFGRKIVLFVTMAIQTLFTVV 188

  Fly   276 TSMSTDFFTFAISRFLVGASYDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFTMVMPWIAL 340
            ...|..:..|....|:||....:.:...::|.:|.:....|.:.:.|.:.||:|...|::|..|.
Zfish   189 QVFSPSWQIFCFLFFIVGMGQISNYVAAFVLGMEILSSSVRDVYSTLGVCLFFSIGYMILPLAAF 253

  Fly   341 SAGNWRRFSSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKKQVSKEILDLF 405
            ...:||......::|....:..:..:|||.|||:|.|.:.:|..|::...::|:......|..|.
Zfish   254 FLRDWRSLMLALTIPGFFYIPLWWFIPESPRWLLSQGRVQEAEAIIRKAAKINRVTAPDVIFPLM 318

  Fly   406 EASCTQFYKEELDG-RDFTVLSIFKRKRMARYMI-LMILIWMSISLVYDGHVRAASVLDSENIFL 468
            :::      |:..| :.|:|..:.|...: |||. |:.||||::|:.|.......|.|.. ||:|
Zfish   319 QST------EDAGGVQSFSVCELLKSSNI-RYMTGLLCLIWMAVSIGYCALSLNTSSLHG-NIYL 375

  Fly   469 FFTIACATELPGNILVILTLDRAGRRWCSFFYTSLSGVFSLLGASF-QNRANMRMS-ALAGRFFS 531
            ...::...|:|..::..|.|..|.||.|.....:|.|:..||.... ::::::.:: .:.|:|..
Zfish   376 NCLLSAVVEVPALLMAWLMLRLAPRRHCLASTLALGGLVLLLILLIPEDQSSVTLALVMLGKFGL 440

  Fly   532 NICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVVYLSKKSLSSTLIVLGALGIFGGL 596
            :..::|.....||:.|||:|...:........|..:.:|...||.....|...|::|.:.:..||
Zfish   441 SAAFSIIYPVTAELYPTVLRNTALGACSMSSRVGGISAPYFNYLGSYHRSLPYILIGGINVLSGL 505

  Fly   597 LALFLPETLNHELPETLSDGAQFGKNQRIWHMPCCGPGSRKSHP 640
            |:..|||:....||||:      |:.|.:       .|.:|..|
Zfish   506 LSFLLPESRGSALPETI------GQMQTV-------KGLKKHSP 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	135/525 (26%)
slc22a21	NP_001295487.1	2A0119	14..521	CDD:273328	135/525 (26%)