Protein Alignment CG10486 and Slc22a23

DIOPT Version :9

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_001028339.1
• Gene: Slc22a23 / 73102
• MGIID: 1920352
• Length: 689
• Species: Mus musculus
• Alignment Length: 629
• Identity: 137/629 - (21%)
• Similarity: 232/629 - (36%)
• Gaps: 154/629 - (24%)

  Fly    94 IDFD-DLLPMIGQF-GRFQIRL-FLFMIPFCFITAFVYLGQIFMCLTPPKYYC----YVPELLHT 151
            :|:| .:||.:|.. |.:|..| .|..||..|| .|......|: |..|.::|    ...||...
Mouse    78 LDYDGSVLPFLGGLGGGYQKTLVVLTWIPALFI-GFSQFSDSFL-LDQPDFWCRGAGKGTELAGA 140

  Fly   152 PVELR--------------------------------KELSIPKEKDGSYSRCRMYNTNYTKIHF 184
            .|..|                                ..|..|..|..:.|.|..:..:|.
Mouse   141 TVTGRWGDMGNWTSPSATPFSTASWGTTSNRSNSSDTPPLPSPPGKGNNDSNCDCHAWDYG---- 201

  Fly   185 AENPSAYINTSLPTIPCKKGYVFEQEGRAFESATMEFGWLCDDDKYATYAQIIFFLGSILGGLAY 249
                   |.|.|                 .::...::..:||:......|:....:|.|.|.|..
Mouse   202 -------IRTGL-----------------IQNVVSKWDLVCDNTWKVHIAKFSLLVGLIFGYLIT 242

  Fly   250 GHFADHCGRVAALVSSCFLALVGSLATSMSTDFFTFAISRFLVGASYDTCFTMVYILVLEYVGPK 314
            |..||..||...|:.|....|:..|..::|.:...|:..||..|.........:|.|.:|...|.
Mouse   243 GCIADWVGRRPVLLFSTIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPG 307

  Fly   315 YR---TLVANLSLALFYSPFTMVMPWIALSAGNWRRFSSFTSLPIVLAMFSFCLLPESARWLVSV 376
            .|   |:||  |.......|  :||.:|....:|:...:....|.:|.:..:.:.|||.|||::.
Mouse   308 KRFIITMVA--SFVAMAGQF--LMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMAT 368

  Fly   377 GEIDKALEIL-----KNVI--EVNKKQVSKEILDLFEASCTQFYKEELDGRDFTVLSIFKRKRMA 434
            .:.:.|.:::     ||.:  |.:.|.|..|:            ::||.            :|..
Mouse   369 QQFESAKKLILYLTQKNCVSPESDIKGVMPEL------------EKELS------------RRPK 409

  Fly   435 RYMILMIL----IWMSI------SLVYDG--HVRAASVLDSE-----------NIFLFFTIACAT 476
            :..|:.::    :|.:|      ||...|  |..|.|::..|           :.:...:||.|:
Mouse   410 KVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTMASIALAS 474

  Fly   477 ELPGNILVILTLDRAGRRWCSFFYTSLS-----GVFSLLG-------ASFQNRANMRMS------ 523
            .| ...||:..|.|.|........|:|:     |:.:|:|       :..|.:..:.||
Mouse   475 CL-AMCLVVKFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSELQLKLAVGMSDSVKDK 538

  Fly   524 -----ALAGRFFSNICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVVYLSKKSLSST 583
                 ::.|.|.|:...::.:.:.|||.|||:|..|:..:.......||.:|.:...::|.....
Mouse   539 FSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLH 603

  Fly   584 LIVLGALGIFGGLLALFLPETLNHELPETLSDGAQFGKNQRIWH 627
            .|:.....:...:..|.|||:.|..|||.:::|..:.:...:.|
Mouse   604 HIIFACCTLICIICILLLPESRNQNLPENIANGEHYTRQPLLPH 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	130/601 (22%)
		MFS	231..602	CDD:119392	95/426 (22%)
Slc22a23	NP_001028339.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		2A0119	98..631	CDD:273328	126/591 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..188		3/25 (12%)
		MFS	230..>359	CDD:119392	34/132 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843360
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.030