Protein Alignment CG10486 and Slc22a23

DIOPT Version :9

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_072146.1
• Gene: Slc22a23 / 64559
• RGDID: 620302
• Length: 689
• Species: Rattus norvegicus
• Alignment Length: 610
• Identity: 137/610 - (22%)
• Similarity: 240/610 - (39%)
• Gaps: 116/610 - (19%)

  Fly    94 IDFD-DLLPMIGQF-GRFQIRL-FLFMIPFCFITAFVYLGQIFMCLTPPKYYCY----VPELLHT 151
            :|:| .:||.:|.. |.:|..| .|..||..|| .|......|: |..|.::|:    ..||...
  Rat    78 LDYDGSVLPFLGGLGGGYQKTLVVLTWIPALFI-GFSQFSDSFL-LDQPNFWCHGAGKGTELAGA 140

  Fly   152 PVELR----KELSIPKEKDGSYSRCRMYNTNYTKIHFAENPSAYINTSLPTIPCKKGYVFEQEGR 212
            .|..|    ...:.|.....|.:   .:.|...:.:.::.|      .||:.|.|.......|..
  Rat   141 TVTGRWGDMGNWTSPSATPFSTA---SWGTTSNRSNSSDTP------PLPSPPGKGNNDSNCECH 196

  Fly   213 AF---------ESATMEFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFL 268
            |:         ::...::..:||:......|:....:|.|.|.|..|..||..||...|:.|...
  Rat   197 AWDYGIRTGLVQNVVSKWDLVCDNAWKVHVAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSVIF 261

  Fly   269 ALVGSLATSMSTDFFTFAISRFLVGASYDTCFTMVYILVLEYVGPKYR---TLVANLSLALFYSP 330
            .|:..|..::|.:...|:..||..|.........:|.|.:|...|..|   |:||  |.......
  Rat   262 ILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFIITMVA--SFVAMAGQ 324

  Fly   331 FTMVMPWIALSAGNWRRFSSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEIL-----KNVI 390
            |  :||.:|....:|:...:....|.:|.:..:.:.|||.|||::..:.:.|.:::     ||.:
  Rat   325 F--LMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKKLILYLTQKNCV 387

  Fly   391 --EVNKKQVSKEILDLFEASCTQFYKEELDGRDFTVLSIFKRKRMARYMILMIL----IWMSI-- 447
              |.:.|.|..|:            ::||.            :|..:..|:.::    :|.:|
  Rat   388 SPESDIKGVMPEL------------EKELS------------RRPKKVCIVKVVGTRNLWKNIVV 428

  Fly   448 ----SLVYDG--HVRAASVLDSE-----------NIFLFFTIACATELPGNILVILTLDRAGRRW 495
                ||...|  |..|.|::..|           :.:...:||.|:.| ...||:..|.|.|...
  Rat   429 LCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTMASIALASCL-AMCLVVRFLGRRGGLL 492

  Fly   496 CSFFYTSLS-----GVFSLLG-------ASFQNRANMRMS-----------ALAGRFFSNICYNI 537
            .....|:|:     |:.:|:|       :..|.:..:.||           ::.|.|.|:...::
  Rat   493 LFMILTALASLLQLGLLNLIGKYSQHPDSELQLKLAVGMSDSVKDKFSIAFSIVGMFASHAVGSL 557

  Fly   538 GLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVVYLSKKSLSSTLIVLGALGIFGGLLALFLP 602
            .:.:.|||.|||:|..|:..:.......||.:|.:...::|......|:.....:...:..|.||
  Rat   558 SVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLP 622

  Fly   603 ETLNHELPETLSDGAQFGKNQRIWH 627
            |:.:..|||.:::|..:.:...:.|
  Rat   623 ESRDQNLPENIANGEHYTRQPLLSH 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	130/582 (22%)
		MFS	231..602	CDD:119392	95/426 (22%)
Slc22a23	NP_072146.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..188		6/34 (18%)
		MFS_SLC22A23	187..608	CDD:341002	98/449 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346874
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.030