Protein Alignment CG10486 and Slc22a4

DIOPT Version :10

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_071606.1
• Gene: Slc22a4 / 64037
• RGDID: 621149
• Length: 553
• Species: Rattus norvegicus
• Alignment Length: 559
• Identity: 134/559 - (23%)
• Similarity: 242/559 - (43%)
• Gaps: 51/559 - (9%)

  Fly    95 DFDDLLPMIGQFGRFQIRLFLFMIPFCFI-TAFVYLGQIFMCLTPPKYYCYVPELLHTPVELRKE 158
            |:|:::..:|.:|.|| ||..|::....| ..|..:..:|:..| |::.|.||..::.....|..
  Rat     3 DYDEVIAFLGDWGPFQ-RLIFFLLSASIIPNGFNGMSVVFLAGT-PEHRCLVPHTVNLSSAWRNH 65

  Fly   159 LSIPKE-KDGSY--SRCRMYN----TNYTKIHFAENPSAYIN-TSLPTIPCKKGYVFEQEGRAFE 215
             |||.| |||..  ..||.|.    .|::.:..  .|...:: ..|....|..|:.:.::  .|.
  Rat    66 -SIPLETKDGRQVPQSCRRYRLATIANFSALGL--EPGLDVDLEQLEQESCLDGWEYSKD--VFL 125

  Fly   216 SATM-EFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFLALVGSLATSMS 279
            |..: |:..:|:||........:||:|.:.|....|..:|..||...|.::..:....|.....|
  Rat   126 STIVTEWNLVCEDDWKTPLTTSLFFVGVLCGSFVSGQLSDRFGRKKVLFATMAVQTGFSFVQIFS 190

  Fly   280 TDFFTFAISRFLVGASYDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFTMVMPWIALSAGN 344
            |::..|.:...:||....:.:.:.:||..|.:....|.|.:.|.:..|::...||:|..|....:
  Rat   191 TNWEMFTVLFAIVGMGQISNYVVAFILGTEILSKSVRILFSTLGVCTFFAIGYMVLPLFAYFIRD 255

  Fly   345 WRRFSSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKKQVSKEILDLFEASC 409
            ||......:||.:..:..:..:|||.|||:|....::|.:|::...::|.......|.|..|...
  Rat   256 WRMLLLALTLPGLFCVPLWWFIPESPRWLISQRRFEEAEQIIQKAAKMNGIMAPAVIFDPLELQE 320

  Fly   410 TQFYKEELDGRDFTVLSIFKRKRMARYMILMILIWMSISLVYDGHVRAASVLDSEN----IFLFF 470
            ....|::    ...:|.:||.:.:|...::.:::||..|:.|     .|..|:..|    ::|..
  Rat   321 LNSLKQQ----KVFILDLFKTRNIATITVMSVMLWMLTSVGY-----FALSLNVPNLHGDVYLNC 376

  Fly   471 TIACATELPGNILVILTLDRAGRRWCSFFYTSLSGVFSLLGASF---------QNRANMRMSALA 526
            .::...|:|......|.|....||:.      ::||....|...         .|..::.: .:.
  Rat   377 FLSGLIEVPAYFTAWLLLRTLPRRYI------IAGVLFWGGGVLLLVQVVPEDYNFVSIGL-VML 434

  Fly   527 GRFFSNICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVVYLSKKSLSSTLIVLGALG 591
            |:|.....:::...:.||:.||:||...|........|..:::|..|||...:.....|::|:|.
  Rat   435 GKFGVTSAFSMLYVFTAELYPTLVRNMAVGITSMASRVGSIIAPYFVYLGAYNRLLPYILMGSLT 499

  Fly   592 IFGGLLALFLPETLNHELPETLSD-----GAQFGKNQRI 625
            :..|::.||.||:....|||.|..     |.:.||...:
  Rat   500 VLIGIITLFFPESFGVTLPENLEQMQKVRGFRCGKKSTV 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	127/530 (24%)
Slc22a4	NP_071606.1	2A0119	12..519	CDD:273328	126/529 (24%)