Protein Alignment CG10486 and Slc22a17

DIOPT Version :10

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_001347335.2
• Gene: Slc22a17 / 59049
• MGIID: 1926225
• Length: 627
• Species: Mus musculus
• Alignment Length: 596
• Identity: 142/596 - (23%)
• Similarity: 225/596 - (37%)
• Gaps: 103/596 - (17%)

  Fly    94 IDFDDLLPMIGQF-GRFQIRLFLFMIPFCFITAFVYLGQIFMCLTPPKYYCYVPELLHTPVELRK 157
            :.|:.||..:|.. |..|::|.|..:|..|:...:....|| .|.|| .:|:..
Mouse    74 LSFEALLAQVGALGGGQQLQLGLCCLPVLFVALGMASDPIF-TLAPP-LHCHYG----------- 125

  Fly   158 ELSIPKEKDGSYSRCRMYNTNYTKIHFAENPSAYINTSLPTIP------------CKKGYVFEQE 210
              ::|....|..........:......|.:.::.:.||  |.|            |.|.:.:...
Mouse   126 --ALPPNASGWEQPPNSSGVSVAGAALAASAASGVVTS--TDPSCSGFAPPDFNHCLKDWDYNGL 186

  Fly   211 GRAFESATMEFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGR------VAALVSSCFLA 269
            .....:|..::..:||........||:|.||...|.|..|:.||..||      ...||..|.
Mouse   187 PVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCG-- 249

  Fly   270 LVGSLATSMSTDFFTFAISRFLVGASYDTCFTMVYILVLEYVGPKYRTLVANLSLA--------- 325
             ||..|...||.....   |||:|.........||::.||...|..|..||   ||
Mouse   250 -VGGAAAGSSTGIMAL---RFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA---LAGELVGVGGH 307

  Fly   326 -LFYSPFTMVMPWIALSAGNWRRFSSFTSLPIVLAMFSFC--LLPESARWLVSVGEIDKALEILK 387
             ||..        :||.:.:||......:.|.:|.:|...  |..||||||:...:|::|..:|:
Mouse   308 FLFLG--------LALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLR 364

  Fly   388 NVIEVNKK------QVSKEILDLFEASCTQFYKEELDGRDFTVLSIFKRKRMARYMILMILIWMS 446
            .:.|.|:.      :.::|.|...|.:|           .....|.|....:..|.    .||.:
Mouse   365 ILAERNRPHGQMLGEEAQEALQELENTC-----------PLPATSTFSFASLLNYR----NIWKN 414

  Fly   447 ISLVYDGHVRAASVL----------DSENIFLFFTIACATELPGNILVILTLDRAGRRWCSFFYT 501
            :.::...:..|.::.          ...:.:|...:|..|.....:.:.:|:||.|||.......
Mouse   415 LLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSM 479

  Fly   502 SLSGVFS--LLGA-SFQNRANMRMSALAGRFFSNICYNIGLQWAAEILPTVVRAQGVAFIHTMGF 563
            :|:|:.|  |||. .:.|.|.:...::.|.|.|.....:....|:|::||.||.:|:..|..:|.
Mouse   480 TLTGIASLVLLGLWDYLNDAAITTFSVLGLFSSQASAILSTLLASEVIPTTVRGRGLGLIMALGA 544

  Fly   564 VAMLMSPPVVYLSKKSLSSTLIVLGALGIFGGLLALFLPETLNHELPETLSDGAQFGKNQRIWHM 628
            :..|..|..............:||.|..:...|..:.||||....|||.|.|| :..:...:...
Mouse   545 LGGLSCPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDG-ELCRRPSLLRQ 608

  Fly   629 PCCGPGSRKSH 639
            |   |.:|..|
Mouse   609 P---PPNRCDH 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	131/557 (24%)
Slc22a17	NP_001347335.2	MFS_SLC22A17	170..583	CDD:341003	105/444 (24%)