Protein Alignment CG10486 and sv2a

DIOPT Version :9

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: XP_696434.2
• Gene: sv2a / 568033
• ZFINID: ZDB-GENE-131001-1
• Length: 733
• Species: Danio rerio
• Alignment Length: 806
• Identity: 147/806 - (18%)
• Similarity: 238/806 - (29%)
• Gaps: 355/806 - (44%)

  Fly     2 ANDEKG--NASTE---DDDKPKKREHRDQGQQSKLKKIKYYIEPDKVDIGIQAGDSLEKVKVTYV 61
            |||::|  :.|||   :||:..:.|::                      ||...||:||.
Zfish    74 ANDDEGAHSDSTEGHDEDDEIYEGEYQ----------------------GIPRNDSVEKA----- 111

  Fly    62 EPDDEESSHGFFWGKKKSETSLPRRSWETDDYIDFDDLLPMIGQFGRFQIRLFLFMIPFC----- 121
              |.:..:.|....:..::....||..:.:....::.:|...|. ||||..|: |::...
Zfish   112 --DRQVGAVGQSQFRDMTQYEGERRKDQEELAQQYETILQECGH-GRFQWTLY-FVLGLALMADG 172

  Fly   122 ---FITAFVY-LGQIFMCLTPPKYYCYVPELLHTPVELRKELSIPKEKDGSYSRCRMYNTNYTKI 182
               |:..||. ..:..|||:.|
Zfish   173 VEIFVVGFVLPSAEKDMCLSEP------------------------------------------- 194

  Fly   183 HFAENPSAYINTSLPTIPCKKGYVFEQEGRAFESATMEFGWLCDDDKYATYAQIIFFLGSILGGL 247
                               .||.:                            .:|.:||.::|..
Zfish   195 -------------------NKGML----------------------------GLIVYLGMMVGAF 212

  Fly   248 AYGHFADHCGRVAALVSSCFLALVGSLATSMSTDFFTFAISRFLVGASYDTCFTMVYILVLEYVG 312
            .:|..||..||...|:.|..:..|.:..:|....:.:|...|.|.|........:|:....|::.
Zfish   213 VWGGLADRIGRRQTLLISLSINSVFAFFSSFVQGYSSFLFCRLLSGVGIGGSIPIVFSYYSEFLA 277

  Fly   313 PKYRTLVANLS-LALFY---SPFTMVMPWI-------------ALSAGNWRRFSSFTSLPIVLAM 360
            .:.|.  .:|| |.:|:   ..:...|.|.             |....:||.|....:.|.|.|:
Zfish   278 QEKRG--EHLSWLCMFWMIGGIYAAAMAWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVAAI 340

  Fly   361 FSFCLLPESARWLVSVGEIDKALEILKNVIEVNK------------------KQVSKEILDL--- 404
            .:...:|||.|:.:..|:.|:|..|||.|.:.|.                  ||:. |::|:
Zfish   341 AALTTMPESPRFYLENGKHDEAWMILKQVHDTNMRAKGYPERVFSVTTIKTVKQMD-ELVDMGGE 404

  Fly   405 -------FEASCTQFYKEELDGRDFTVLSIFKRKRMARYMILMILIWMSISLVYDG--------- 453
                   :....|..: .::.|...||.:  ...|...||  |:.:|.|:|..|.|
Zfish   405 ATAWHQRWRIKLTNLF-HQVWGNFLTVFN--PEYRRITYM--MMAVWFSMSFSYYGLTVWFPDMI 464

  Fly   454 ---------------------HVRAASVLD----------------------------------- 462
                                 ||.....|:
Zfish   465 KYLQKQEYSSRTKVFIKEKVEHVTFNFTLENQIHRNGEYFNNKFLNLKMKSMVFEDSLFEECYFE 529

  Fly   463 ---SENIF---------LFFTI----------------------ACATE---------------- 477
               |.|.|         ||:..                      .|..:
Zfish   530 DITSSNTFFRNCTFISTLFYNTDLFKYRLINSKLINSTFLHNKEGCMLDFSDENNAYMIYFVSFL 594

  Fly   478 -----LPGNILVILTLDRAGRRWCSFFYTSLSG--VFSLLGASFQNRANMRMSALAGRFFSNICY 535
                 |||||:..|.:|:.||      ...|:|  |.|.:...|.:..|...:.:|     .:|.
Zfish   595 GTLAVLPGNIVSALLMDKIGR------LRMLAGSSVISCVSCFFLSFGNSESAMIA-----LLCL 648

  Fly   536 NIGL---QWAA------EILPTVVRAQGVAFIHTM-------------GFVAMLMSPPVVYLSKK 578
            ..|:   .|.|      |:.|:..|.....|::.:             .||.:..:.|:::.|
Zfish   649 FGGISIASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFQSFVGITKAVPILFAS-- 711

  Fly   579 SLSSTLIVLGALGIFGGLLALFLPET 604
                     |||.. |..|||.||||
Zfish   712 ---------GALAA-GSFLALKLPET 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	126/699 (18%)
		MFS	231..602	CDD:119392	106/559 (19%)
sv2a	XP_696434.2	synapt_SV2	1..733	CDD:130366	147/806 (18%)
		MFS	162..725	CDD:119392	116/683 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910